Positive Mixed lymphocyte Culture Test Result Due to HLA-DP Mismatch
Küçük Resim Yok
Tarih
2011
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Galenos Publ House
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Graft Versus Host Disease (GVHD) remains a major cause of morbidity and mortality in allogeneic stem cell transplantation (SCT). The MLC assay has been generally accepted as a standard test for determining HLA-D region compatibility. In this study, the MLC test has been carried out on the related recipient-donor couple who were prepared for allogeneic SCT and were found to be matched for HLA-A, -B, -Cw, DR, DO but not for -DP. The result of the MLC test was positive. We observed that HLA-DP mismatch was responsible for the increased proliferation values in MLC test.
Açıklama
Anahtar Kelimeler
Mixed Lymphocyte Culture, HLA-DP, Stem Cell Transplantation, Marrow-Transplantation, Unrelated Donors, Selection
Kaynak
Balkan Medical Journal
WoS Q Değeri
N/A
Scopus Q Değeri
Q3
Cilt
28
Sayı
2
