Normalization of negative T waves in the chronic stage of Q wave anterior myocardial infarction as a predictor of myocardial viability

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dc.authoridAltun, Armagan/0000-0002-3233-8263
dc.authoridgültekin, aziz/0000-0002-0311-8077
dc.authoridDURMUS ALTUN, GULAY/0000-0002-1822-9386
dc.authorwosidAltun, Armagan/ABB-5844-2020
dc.authorwosidgültekin, aziz/Q-9820-2018
dc.authorwosidDURMUS ALTUN, GULAY/S-6586-2016
dc.contributor.authorAltun, A
dc.contributor.authorDurmus-Altun, G
dc.contributor.authorBirsin, A
dc.contributor.authorGultekin, A
dc.contributor.authorTatli, E
dc.contributor.authorOzbay, G
dc.date.accessioned2024-06-12T11:08:55Z
dc.date.available2024-06-12T11:08:55Z
dc.date.issued2005
dc.departmentTrakya Üniversitesien_US
dc.description.abstractWe investigated whether spontaneous normalization of negative T waves ( TWN) on infarct-related ECG leads ( IRLs) in the chronic phase of Q wave anterior myocardial infarction ( MI) could be a predictor of residual viability in infarct areas. We prospectively studied 35 patients ( age 60 +/- 8.6 years) in the chronic phase of Q wave anterior MI. Spontaneous TWN ( group A, n = 23) were defined as negative T waves that became upright ( greater than or equal to0.15 mV) in 62 IRLs. The presence of negative T waves ( group B, n = 12) was defined as symmetric or biphasic negative T wave of greater than or equal to0.15 mV. All patients underwent same-day rest Tl-201-stress Tc-99m sestamibi dual-isotope myocardial perfusion SPECT and 24-hour Tl-201 reinjection imaging for ischemia and viability analysis. On scintigraphic examination, ischemic or viable myocardial segments were found in 18 patients ( 78%) with TWN and 4 patients ( 33%) of group B ( p = 0.013). The use of TWN as a parameter had a marked influence on the sensitivity ( 82%), specificity ( 62%), positive ( 78%) and negative ( 67%) predictive values and accuracy ( 74%) of the diagnosis of viable smyocardium. If we add the criterion of positive T waves in aVR with negative T waves to our criteria, we found that sensitivity ( 90%), positive ( 80%) and negative ( 80%) predictive values and accuracy ( 80%) increased. The results of our study suggest that analysis of TWN on IRLs is an accurate marker of residual viability and/or persistent peri-infarct ischemia in patients in the chronic stage of Q wave anterior MI, and therefore optimizes the diagnostic and therapeutic strategies after MI. Copyright (C) 2005 S. Karger AG, Basel.en_US
dc.identifier.doi10.1159/000082051
dc.identifier.endpage78en_US
dc.identifier.issn0008-6312
dc.identifier.issue2en_US
dc.identifier.pmid15539785en_US
dc.identifier.scopus2-s2.0-14044276259en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage73en_US
dc.identifier.urihttps://doi.org/10.1159/000082051
dc.identifier.urihttps://hdl.handle.net/20.500.14551/22608
dc.identifier.volume103en_US
dc.identifier.wosWOS:000226899200004en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofCardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMyocardial Infarctionen_US
dc.subjectT Wave Normalizationen_US
dc.subjectScintigraphyen_US
dc.subjectViability, Myocardialen_US
dc.subjectLeadsen_US
dc.subjectEchocardiographyen_US
dc.subjectImprovementen_US
dc.titleNormalization of negative T waves in the chronic stage of Q wave anterior myocardial infarction as a predictor of myocardial viabilityen_US
dc.typeArticleen_US

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