Nutritional vitamin B12 deficiency presenting as bicytopenia in an infant

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Tarih

2006

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Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

In infancy, vitamin B12 deficiency is usually secondary to maternal deficiency, especially in their exclusively breastfed infants. Here, an 8-month-old male infant admitted for bicytopenia and developmental delay is presented. On admission the patient was pale, apathic, hypotonic and lethargic. He had severe anaemia (Hb 6.2 g/dl) and thrombocytopenia (65×10 9/l). Serum vitamin B12 levels of the infant and his mother were low and in bone marrow aspiration, megaloblastic changes were observed. A rapid response in haematological values was observed after commencement of vitamin B12 treatment. Vitamin B12 deficiency should be considered in the differential diagnosis of hypotonic infants with developmental delay accompanied by megaloblastic anaemia. Adequate nutrition of pregnant and nursing mothers must be emphasized. Copyright © Hellenic Society of Haematology.

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Anahtar Kelimeler

Bicytopenia; Infant Nutrition; Megaloblastic Anemia; Vitamin B12 Deficiency, Cyanocobalamin; Anamnesis; Article; Bicytopenia; Blood Analysis; Blood Cell Count; Bone Marrow Biopsy; Case Report; Clinical Feature; Cyanocobalamin Deficiency; Cytopenia; Disease Association; Human; Infant; Infant Nutrition; Male; Megaloblastic Anemia; Physical Examination; Thrombocytopenia; Vitamin Blood Level

Kaynak

HAEMA

WoS Q Değeri

Scopus Q Değeri

N/A

Cilt

9

Sayı

3

Künye