99mTc-dimercaptosuccinic acid scan versus MRI in pyelonephritis: a meta-analysis

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dc.authoridSarikaya, Ismet/0000-0002-1087-580X
dc.authorwosidSarikaya, Ismet/G-7881-2015
dc.contributor.authorSarikaya, Ismet
dc.contributor.authorAlbatineh, Ahmed N.
dc.contributor.authorSarikaya, Ali
dc.date.accessioned2024-06-12T10:50:13Z
dc.date.available2024-06-12T10:50:13Z
dc.date.issued2020
dc.departmentTrakya Üniversitesien_US
dc.description.abstractPurpose Tc-99m-dimercaptosuccinic acid (DMSA) scan is the current gold standard in detecting parenchymal changes, particularly scarring, in pyelonephritis. Recently, magnetic resonance imaging (MRI) is gaining popularity in the diagnosis of pyelonephritis. The aim of this study is to perform a meta-analysis on studies directly comparing MRI to DMSA scan in patients with pyelonephritis. Materials Systematic searches of PUBMED and EMBASE databases were performed to extract studies comparing MRI and DMSA scan in patients with pyelonephritis. The relevance of articles was assessed by two authors according to predefined inclusion and exclusion criteria. The pooled estimates of the sensitivities of MRI and DMSA scan were computed using random-effects meta-analysis model following DerSimonian and Laird's method. Subgroup analysis and publication bias were performed. Results Seven studies were included (164 patients). Using random effect model, the pooled estimate of the sensitivities of MRI and DMSA scan were 0.62 (95%CI: 0.44 - 0.77) and 0.59 (95%CI: 0.48 - 0.70), respectively. The pooled estimates of sensitivities of MRI and DMSA scan for acute pyelonephritis were 0.73 (95%CI: 0.49- 0.89) and 0.66 (95%CI: 0.56 - 0.75), respectively, and for scar detection were 0.48 (95%CI: 0.31- 0.66), and 0.50 (95%CI: 0.30 - 0.71), respectively. Conclusion The overall sensitivities of MRI and DMSA scan were equivalent in detecting parenchymal changes in pyelonephritis. MRI and DMSA scan appeared to be equivalent to scar detection. In a small number of studies, MRI appeared to be better than the DMSA scan in acute pyelonephritis but this should be further studied in a larger number of patients.en_US
dc.identifier.doi10.1097/MNM.0000000000001270
dc.identifier.endpage1152en_US
dc.identifier.issn0143-3636
dc.identifier.issn1473-5628
dc.identifier.issue11en_US
dc.identifier.pmid32796453en_US
dc.identifier.scopus2-s2.0-85093538703en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1143en_US
dc.identifier.urihttps://doi.org/10.1097/MNM.0000000000001270
dc.identifier.urihttps://hdl.handle.net/20.500.14551/17916
dc.identifier.volume41en_US
dc.identifier.wosWOS:000581850500005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofNuclear Medicine Communicationsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject99mtc-Dimercaptosuccinic Acid Scanen_US
dc.subjectPyelonephritisen_US
dc.subjectMeta-Analysisen_US
dc.subjectMRIen_US
dc.subjectRenal Cortical Scintigraphyen_US
dc.subjectMagnetic-Resonance Urographyen_US
dc.subjectTc-99m-Dmsa Scintigraphyen_US
dc.subjectChildrenen_US
dc.subjectGadoliniumen_US
dc.subjectDiagnosisen_US
dc.subjectDefectsen_US
dc.subjectSpecten_US
dc.subjectIdentificationen_US
dc.subjectSonographyen_US
dc.title99mTc-dimercaptosuccinic acid scan versus MRI in pyelonephritis: a meta-analysisen_US
dc.typeArticleen_US

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