Comparison of interpleural bupivacaine plus adrenaline to bupivacaine plus adrenaline plus morphine injections in postoperative analgesia

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Tarih

1995

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Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

This study was performed on 20 ASA I-II patients operated with subcostal incision. The cases were divided into two groups to investigate the quality and the time course of two different combinations of analgesics. Interpleurally, bupivacaine (0.5 %, 150 mg) plus adrenaline (1/200.000, 0.15 mg) were administered to group I (n=10), and bupivacaine (0.5 %, 150 mg) pills adrenaline (1/200.000, 0.15 mg) plus morphine (2 mg) were administered to group II (n=10). Forced vital capacity (FVC) and forced expiration volume in the first second (FEV1) were measured before the premedication (stage I) in, both groups. Following surgical intervention; Visual analogue scala (VAS), FVC and FEV1 values were measured before the blockade (stage II), 30 minutes (stage III) and 120 minutes (stage IV) after the blockade respectively in both groups. In both groups, 1) VAS values decreased significantly at stages III and IV. 2) FVC and FEV1 values were found lower in stage II than stage I. Although the values obtained in the stages III and IV could not reach the values of stage I, FVC and FEV1 values showed improvement. There were no significant differences between group I and II in terms of VAS, FVC and FEV1. In group II, analgesia started significantly earlier and lasted significantly longer. As a result, interpleural injection of bupivacaine plus adrenaline after subcostal incision produced sufficient analgesia and helped to improve the impaired respiratory functions. An additional dose of morphine (2 mg) to bupivacaine and adrenaline injections (group II) caused analgesia to start earlier and last longer which may be a reason for preference.

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Anahtar Kelimeler

Adrenaline; Bupivacaine; Interpleural Block; Morphine; Postoperative Analgesia, Adrenalin; Bupivacaine; Morphine; Adult; Article; Clinical Article; Controlled Study; Drug Efficacy; Human; Intrapleural Drug Administration; Postoperative Analgesia; Postoperative Pain; Premedication

Kaynak

Turk Anesteziyoloji ve Reanimasyon

WoS Q Değeri

Scopus Q Değeri

N/A

Cilt

23

Sayı

10

Künye