Comparison between normothermic and mild hypothermic cardiopulmonary bypass in myocardial revascularization of patients with left ventricular dysfunction

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dc.authoridYuksel, Volkan/0000-0001-9518-2588
dc.contributor.authorYuksel, V.
dc.contributor.authorCanbaz, S.
dc.contributor.authorEge, T.
dc.date.accessioned2024-06-12T10:55:45Z
dc.date.available2024-06-12T10:55:45Z
dc.date.issued2013
dc.departmentTrakya Üniversitesien_US
dc.description.abstractAims: The aim of this study was to investigate whether normothermic bypass is superior to mild hypothermia in patients with poor left ventricular function. This was achieved by studying defibrillation rates, postoperative requirements of cardiac pacing or other morbidity issues and mortality in patients with left ventricular dysfunction operated upon for elective coronary revascularization. Methods: Data were collected retrospectively from 252 consecutive patients with left ventricular dysfunction (ejection fraction <= 35%) undergoing coronary revascularization between January 2005 and January 2011. Patients operated upon under mild hypothermia (32 degrees C) were placed in Group 1 and under normothermia (>= 35 degrees C) were placed in Group 2. Comorbidities and postoperative complications were recorded. Results: There were 128 patients in Group 1 and 124 patients in Group 2. Plasma concentrations of CK-MB and troponin T peaked at 6 hours postoperatively, with no significant difference between the groups. Despite longer aortic cross-clamp time and total bypass time in Group 2, significantly less defibrillation requirement rates after aortic declamping was observed. Hospital mortality occured in 16 patients; 8 patients in each group. Conclusions: Normothermia enables less requirement for defibrillation after aortic declamping and postoperative cardiac pacing in patients with left ventricular dysfunction, which may be interpreted as better myocardial protection under normothermic bypass. However, maintaining normothermia had no effect on postoperative stroke, postoperative atrial fibrillation, renal failure development and mortality.en_US
dc.identifier.doi10.1177/0267659113483798
dc.identifier.endpage423en_US
dc.identifier.issn0267-6591
dc.identifier.issn1477-111X
dc.identifier.issue5en_US
dc.identifier.pmid23563895en_US
dc.identifier.scopus2-s2.0-84882991020en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage419en_US
dc.identifier.urihttps://doi.org/10.1177/0267659113483798
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19543
dc.identifier.volume28en_US
dc.identifier.wosWOS:000323311800008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofPerfusion-Uken_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCardiopulmonary Bypassen_US
dc.subjectCoronary Artery Bypassen_US
dc.subjectHeart Failureen_US
dc.subjectNormothermiaen_US
dc.subjectMild Hypothermiaen_US
dc.subjectLong-Term Survivalen_US
dc.subjectCoronary Revascularizationen_US
dc.subjectSurgeryen_US
dc.titleComparison between normothermic and mild hypothermic cardiopulmonary bypass in myocardial revascularization of patients with left ventricular dysfunctionen_US
dc.typeArticleen_US

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