Medical management of ectopic pregnancy with extremely high ?-HCG levels: A case report

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Tarih

2004

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Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

We report the successful treatment of an unruptured ectopic pregnancy in a patient with extremely high ?-human chorionic gonadotropin concentrations. A 33-year-old woman, gravida 2, para 0, abortus 1, presented to our department due to menstrual delay. On transvaginal ultrasonography, she had an unruptured ectopic pregnancy (3.5 × 4.5 cm). Her initial ?-HCG concentration was 38,270 mIU/ml. The administration of methotrexate (50 mg/m2) was performed intramuscularly. Serum ?-HCG levels decreased > 15% between post-therapy days 4 (31,324 mIU/ml) and 7 (13,108 mIU/ml), and did not rise during the subsequent weekly controls. In selected cases with unruptured ectopic pregnancy and extremely high initial ?-HCG levels, medical management with a single-dose methotrexate regimen may be successful.

Açıklama

Anahtar Kelimeler

High ?-Hcg; Methotrexate; Unruptured Ectopic Pregnancy, Chorionic Gonadotropin Beta Subunit; Methotrexate; Adult; Article; Case Report; Color Ultrasound Flowmetry; Disease Course; Dizziness; Ectopic Pregnancy; Female; Hormone Blood Level; Hospital Admission; Human; Menstruation Disorder; Nausea; Transvaginal Echography; Treatment Outcome; Abortifacient Agents, Nonsteroidal; Adult; Chorionic Gonadotropin, Beta Subunit, Human; Female; Humans; Injections, Intramuscular; Methotrexate; Pregnancy; Pregnancy, Ectopic

Kaynak

Clinical and Experimental Obstetrics and Gynecology

WoS Q Değeri

Scopus Q Değeri

Q4

Cilt

31

Sayı

3

Künye