Meperidine versus valethamate bromide in shortening the duration of active labor

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dc.authorwosidYilmaz, Bulent/HKE-5048-2023
dc.authorwosidkart, cavit/F-8844-2012
dc.authorwosidYilmaz, Bulent/GPK-8613-2022
dc.contributor.authorYilmaz, Bulent
dc.contributor.authorKart, Cavit
dc.contributor.authorKelekci, Sefa
dc.contributor.authorGokturk, Umut
dc.contributor.authorSut, Necdet
dc.contributor.authorTarlan, Nurten
dc.contributor.authorMollamahmutoglu, Leyla
dc.date.accessioned2024-06-12T10:50:17Z
dc.date.available2024-06-12T10:50:17Z
dc.date.issued2009
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective: To compare the efficacy and safety of meperidine hydrochloride and valethamate bromide against placebo in shortening the duration of active labor. Method: We randomly assigned 160 nulliparous women with a singleton pregnancy at term who needed induction of labor to one of 3 treatments: 50 mg of meperidine (n = 53), 16 mg of valethamate bromide (n = 53), or a normal saline solution as placebo (n = 54). All medications were given by slow intravenous infusion. Labor duration was the main outcome measure. Results: The intervals between infusion and complete cervical dilation and between infusion and delivery were significantly reduced (P<0.001 and P<0.01) in the meperidine group (103.0 +/- 64.5 minutes and 119.8 +/- 70.2 minutes), in contrast to the placebo group (173.9 +/- 74.8 minutes and 192.2 +/- 82.8 minutes). However, differences were not significant between the 2 treatment groups (139.6 +/- 63.1 minutes and 160.6 +/- 71.9 minutes), or between the valethamate bromide and the placebo group. Conclusion: Meperidine, but not valethamate bromide, significantly shortened the duration of active labor in nulliparous women with a singleton pregnancy at term. (C) 2009 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.ijgo.2009.06.021
dc.identifier.endpage129en_US
dc.identifier.issn0020-7292
dc.identifier.issue2en_US
dc.identifier.pmid19664769en_US
dc.identifier.scopus2-s2.0-70449522993en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage126en_US
dc.identifier.urihttps://doi.org/10.1016/j.ijgo.2009.06.021
dc.identifier.urihttps://hdl.handle.net/20.500.14551/17951
dc.identifier.volume107en_US
dc.identifier.wosWOS:000271178100012en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofInternational Journal Of Gynecology & Obstetricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcceleration Of Laboren_US
dc.subjectDuration Of Laboren_US
dc.subjectMeperidineen_US
dc.subjectValethamate Bromideen_US
dc.subjectRandomized Controlled-Trialen_US
dc.subjectDrotaverine Hydrochlorideen_US
dc.subjectOxytocinen_US
dc.subjectAccelerationen_US
dc.subjectAugmentationen_US
dc.subjectCortisolen_US
dc.subjectDystociaen_US
dc.titleMeperidine versus valethamate bromide in shortening the duration of active laboren_US
dc.typeArticleen_US

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