Reversible hepatocerebral degeneration-like syndrome due to portovenous shunts

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dc.authorscopusid26434237600
dc.authorscopusid55931238700
dc.authorscopusid7003391634
dc.authorscopusid56214353000
dc.contributor.authorGüler S.
dc.contributor.authorUtku U.
dc.contributor.authorTezel A.
dc.contributor.authorÜnlü E.
dc.date.accessioned2024-06-12T10:27:55Z
dc.date.available2024-06-12T10:27:55Z
dc.date.issued2013
dc.description.abstractAtaxia and tremor are rare manifestations of hepatocerebral degeneration due to portovenous shunts. Ammonia is a neurotoxin that plays a significant role in the pathogenesis of hepatic encephalopathy. A 58-year old male patient was assessed with the complaints of gait disturbance, hand tremor, and impairment of speech. His neurological examination revealed dysarthric speech and ataxic gait. Bilateral kinetic tremor was noted, and deep tendon reflexes of the patient were hyperactive. Serum ammonia level was found to be 156.9 ?g/dL. Cranial magnetic resonance (MR) imaging revealed increased signal intensity in bilateral globus pallidus on T1-weighted axial sections, and bilateral prominent hyperintense lesions in the middle cerebellar peduncles on T2-weighted axial sections. On his abdominal MR portography, multiple portohepatic venous collaterals were noted in the right and left lobes of liver parenchyma in 2D FIESTA axial MR sections. To our knowledge, we reported the first case of acquired hepatocerebral degeneration presenting with cerebral symptoms without any hepatic findings in which clinical improvement was noted, and hyperammonemia disappeared following medical treatment.en_US
dc.identifier.endpage426en_US
dc.identifier.issn0019-1442
dc.identifier.issue11.Araen_US
dc.identifier.pmid24555244en_US
dc.identifier.scopus2-s2.0-84891941125en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage424en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/16981
dc.identifier.volume66en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofIdeggyogyaszati Szemleen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHepatocerebral Degeneration; Portovenous Shunt; Prognosis; Treatmenten_US
dc.subjectAdult; Article; Blood Vessel Shunt; Case Report; Dysarthria; Echography; Flapping Tremor; Gait Disorder; Gastrointestinal Endoscopy; Hand Tremor; Human; Hypotension; Liver Function Test; Male; Middle Aged; Middle Cerebellar Peduncle; Neurologic Examination; Nuclear Magnetic Resonance Imaging; Portal Phlebography; Portovenous Shunt; Speech Disorder; Tendon Reflex; Unconsciousness; Wilson Disease; Arteriovenous Fistula; Ataxia; Brain; Cerebellum; Dysarthria; Globus Pallidus; Hepatolenticular Degeneration; Humans; Hyperammonemia; Magnetic Resonance Imaging; Male; Middle Aged; Portal Vein; Syndrome; Treatment Outcome; Tremoren_US
dc.titleReversible hepatocerebral degeneration-like syndrome due to portovenous shuntsen_US
dc.typeArticleen_US

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