Synthesis, Structural Analysis, and Biological Activities of Some Imidazolium Salts

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dc.authoridUluçam, Gühergül/0000-0001-6481-8483;
dc.authorwosidUluçam, Gühergül/AAH-2862-2019
dc.authorwosidTurkyilmaz, Murat/AAK-7876-2020
dc.contributor.authorUlucam, Guhergul
dc.contributor.authorTurkyilmaz, Murat
dc.date.accessioned2024-06-12T11:19:02Z
dc.date.available2024-06-12T11:19:02Z
dc.date.issued2018
dc.departmentTrakya Üniversitesien_US
dc.description.abstractFour newly synthesized imidazolium salts were characterized by nuclear magnetic resonance, vibrational spectra, and mass spectra. Then, the density functional theory calculations were performed to obtain the molecular configurations on which the theoretical nuclear magnetic resonance and infrared spectra were consequently obtained. The comparison of calculated spectra with the experimental spectra for each molecule leads to the conclusion that the theoretical results can be assumed to be a good approach to their molecular configurations. The in vitro biological activities of the salts on the selected bacteria and cancer cell lines were determined by using the broth dilution method according to Clinical and Laboratory Standards Institute guidelines. The 1,3-bis(2-hydroxyethyl) imidazolidinium bromide and 3-(2-ethoxy-2-oxoethly)-1-(3-aminopropyl)-1H-imidazol-3-ium bromide showed efficiency on Bacillus cereus ATCC 11778. The 3-bis(2-carboxyethyl)-4-methyl-1-H-imidazol-3-ium bromide was effective on HeLa wiiile a similar effect was observed on Hep G2 with 3-(2-carboxyethyl)-1-(3-aminopropyl)-1H-imidazol-3-ium bromide.en_US
dc.identifier.doi10.1155/2018/1439810
dc.identifier.issn1565-3633
dc.identifier.issn1687-479X
dc.identifier.pmid29951087en_US
dc.identifier.scopus2-s2.0-85048115616en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1155/2018/1439810
dc.identifier.urihttps://hdl.handle.net/20.500.14551/25056
dc.identifier.volume2018en_US
dc.identifier.wosWOS:000434208000001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherHindawi Ltden_US
dc.relation.ispartofBioinorganic Chemistry And Applicationsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHeterocyclic Carbene Ligandsen_US
dc.subjectFt-Iren_US
dc.subjectInfrared-Spectraen_US
dc.subjectRaman-Spectraen_US
dc.subjectAb-Initioen_US
dc.subjectQuinuclidineen_US
dc.subjectDerivativesen_US
dc.subjectComplexesen_US
dc.subjectRingen_US
dc.titleSynthesis, Structural Analysis, and Biological Activities of Some Imidazolium Saltsen_US
dc.typeArticleen_US

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