Antithrombotic and Anticoagulant Usage Policies
Küçük Resim Yok
Tarih
2010
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Aves Yayincilik, Ibrahim Kara
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Heparin, heparin-derived compounds and warfarin have been successfully used for the prevention and treatment of venous thromboembolism during last 50 years. Low-molecular-weight heparins are alternative drugs to unfractionated heparin because of pharmacokinetic and pharmacodynamic features nowadays. Warfarin is still a gold standard anticoagulant oral agent. However, there are some limitations of these mentioned drugs. It is needed the new oral and parenteral anticoagulant drugs to solve these limitations. There are several preclinical and clinical studies on efficacy and safety of new drugs such as parenteral FXa inhibitors (idraparinux and idraparinux-biotin complex) and oral FXa inhibitor (rivaroxaban-Xiralto) and oral Flla inhibitor (dabigatran-Pradaxa). Both rivaroxaban and clabigatran are newly approved for short term usage on the prevention of VTE during orthopedic procedures such as hip and knee replacement.
Açıklama
Anahtar Kelimeler
Anticoagulants, Antithrombotics, Venous Thromboembolism, Warfarin, Low Molecular Weight Heparins, Deep-Vein-Thrombosis, Venous Thromboembolism, Duration, Therapy
Kaynak
Trakya Universitesi Tip Fakultesi Dergisi
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
27
