The Impacts of miRNAs in Glioblastoma Progression

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dc.authoridKalkan, Rasime/0000-0002-6095-7352
dc.authoridatli, emine ikbal/0000-0001-9003-1449
dc.authorwosidKalkan, Rasime/X-4808-2019
dc.authorwosidatli, emine ikbal/AAN-5060-2020
dc.contributor.authorKalkan, Rasime
dc.contributor.authorAtli, Emine Ikbal
dc.date.accessioned2024-06-12T11:08:39Z
dc.date.available2024-06-12T11:08:39Z
dc.date.issued2016
dc.departmentTrakya Üniversitesien_US
dc.description.abstractmiRNAs are short noncoding RNA sequences that cause translational repression or mRNA degradation. A growing number of studies have sought new biomarkers in GBM that will be important in disease progression and prognosis and as potential therapeutic targets. miRNA-profiling studies in glioblastoma patients have found that aberrant miRNA expression can be used as a target to develop new biomarkers for disease detection and for determining prognosis or therapeutic response. In evaluating the tumor or its therapeutic response, genetic abnormalities such as mutations, epigenetic abnormalities, and aberrant miRNA expressions can be useful markers. This review summarizes the known miRNAs according their therapeutic importance and their use as disease progression biomarkers.en_US
dc.identifier.doi10.1615/CritRevEukaryotGeneExpr.2016015964
dc.identifier.endpage142en_US
dc.identifier.issn1045-4403
dc.identifier.issn2162-6502
dc.identifier.issue2en_US
dc.identifier.pmid27480776en_US
dc.identifier.scopus2-s2.0-84979903071en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage137en_US
dc.identifier.urihttps://doi.org/10.1615/CritRevEukaryotGeneExpr.2016015964
dc.identifier.urihttps://hdl.handle.net/20.500.14551/22492
dc.identifier.volume26en_US
dc.identifier.wosWOS:000380778100004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBegell House Incen_US
dc.relation.ispartofCritical Reviews In Eukaryotic Gene Expressionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMirnaen_US
dc.subjectGBMen_US
dc.subjectGlioblastomaen_US
dc.subjectTherapyen_US
dc.subjectSurvivalen_US
dc.subjectMir-21 Expressionen_US
dc.subjectMicrornasen_US
dc.subjectCanceren_US
dc.subjectCellsen_US
dc.subjectHsa-Mir-181ben_US
dc.subjectAstrocytomaen_US
dc.subjectBiomarkersen_US
dc.subjectSurvivalen_US
dc.subjectGliomasen_US
dc.subjectGrowthen_US
dc.titleThe Impacts of miRNAs in Glioblastoma Progressionen_US
dc.typeArticleen_US

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