Epidural administration of clonidine+bupivacaine and tramadol+bupivacaine combinations during vertebral surgery and assessment of its effect on postoperative analgesia and hemodynamics

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dc.authorscopusid7003369853
dc.authorscopusid6504008476
dc.authorscopusid6603397675
dc.authorscopusid6701467427
dc.contributor.authorMemis D.
dc.contributor.authorMuhittin M.
dc.contributor.authorAlagol A.
dc.contributor.authorPamukcu Z.
dc.date.accessioned2024-06-12T10:28:20Z
dc.date.available2024-06-12T10:28:20Z
dc.date.issued2000
dc.description.abstractThis study was applied on 30 cases to assess the effect of combinations of clonidine+bupivacaine and tramadol+bupivacaine on vital signs. Patients were allocated randomly to one of two groups. Group 1 (n=15) received doses of 1 ?g/kg clonidine+4 mL 0.5 % bupivacaine and Group II (n=15) doses of 75 mg tramadol+4 mL 0.5 % bupivacaine. Mean arterial pressure, heart rate, SpO2, respiratory rate, pain and sedation scores, analgesia onset and side effects were recorded for 24 hours. Statistically there was no difference in mean arterial pressure, heart rate, SpO2, respiratory rate, and sedation scores between Group I and II (p>0.05). Within 1/2. hours, postoperatively there was no difference in VAS between Group I and II (p>0.05). While within the 2,4,6 hours postoperatively there was significant decrease in VAS of Group I (p<0.05). Postoperatively within 12 and 24 hours there were no significant differences detected between two groups (p>0.05). Postoperative onset of analgesia was 6.11±3.19 hours in group I, 4.50±2.09 hours in group II. The difference between two groups was significant (p<0.05). Significant increase in side effects founded in group II was more than group I (p<0.05). We conclude that epidural administrations of clonidine+bupivacaine combination is safe and provide effective analgesia, produces no hemodynamic disturbances, and has no effect on respiratory parameters.en_US
dc.identifier.endpage92en_US
dc.identifier.issn1016-5150
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-0034055769en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage88en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/17177
dc.identifier.volume28en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofTurk Anesteziyoloji ve Reanimasyonen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBupivacaine; Clonidine; Epidural Catheter; Postoperative Analgesia; Tramadol; Vertebral Surgeryen_US
dc.subjectBupivacaine; Clonidine; Tramadol; Article; Clinical Article; Clinical Trial; Controlled Clinical Trial; Controlled Study; Drug Effect; Drug Efficacy; Drug Safety; Epidural Anesthesia; Hemodynamics; Human; Pain Assessment; Postoperative Analgesia; Randomized Controlled Trial; Respiratory Function; Scoring System; Sedationen_US
dc.titleEpidural administration of clonidine+bupivacaine and tramadol+bupivacaine combinations during vertebral surgery and assessment of its effect on postoperative analgesia and hemodynamicsen_US
dc.title.alternativeVertebra cerrahisinde epidural klonidin+bupivakain ve tramadol+bupivakain kombinasyonunun postoperatif analjezi ve hemodinami uzerine etkisien_US
dc.typeArticleen_US

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