Current Status of Postoperative Radiation for Non-Small-Cell Lung Cancer
Küçük Resim Yok
Tarih
2010
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
W B Saunders Co-Elsevier Inc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Radiation therapy can increase local control and potentially improve survival in patients who have had resection for lung cancer. However, radiation therapy also has the potential to cause serious toxicity and should not be indiscriminately delivered. The PORT meta-analysis clearly illustrated the potential toxic effects of postoperative radiotherapy (PORT). Modern three-dimensional radiation treatment planning facilitates the design of treatment fields that more conformally treat the site(s) at risk, and this appears, based on limited data, to improve the therapeutic ratio of PORT. Moreover, systemic and local therapies are likely synergistic, and thus improvements in systemic staging and treatment may increase the ability of local therapies to improve overall survival. Therefore, a reassessment of the utility of postoperative radiation therapy using limited fields and modern techniques is warranted. Semin Radiat Oncol 20:192-200 (C) 2010 Elsevier Inc. All rights reserved.
Açıklama
Anahtar Kelimeler
Dose-Volume Histogram, Resected Stage-Ii, Prophylactic Cranial Irradiation, Vinorelbine Plus Cisplatin, Trialist Association Anita, Randomized-Trial, Thoracic Radiotherapy, Adjuvant Radiotherapy, Dosimetric Factors, Pneumonitis Risk
Kaynak
Seminars In Radiation Oncology
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
20
Sayı
3
