The roles of oxidized low-density lipoprotein and interleukin-6 levels in acute atherothrombotic and lacunar ischemic stroke

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dc.authoridGULDIKEN, Baburhan/0000-0002-9006-1880
dc.authorwosidTurgut, Burhan/A-2517-2016
dc.contributor.authorGuldiken, Baburhan
dc.contributor.authorGuldiken, Sibel
dc.contributor.authorTurgut, Burhan
dc.contributor.authorTurgut, Nilda
dc.contributor.authorDemir, Muzaffer
dc.contributor.authorCelik, Yahya
dc.contributor.authorArikan, Ender
dc.date.accessioned2024-06-12T11:07:18Z
dc.date.available2024-06-12T11:07:18Z
dc.date.issued2008
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThe role of circulating, oxidized low-density lipoprotein and interleukin-6 levels in acute ischemic stroke considering the primary-vessel disease was investigated. The study consisted of 28 patients with acute ischemic stroke and 23 control subjects. Patients were subdivided into large-vessel (n = 12) and small-vessel (n = 16) disease stroke groups according to the Trial of Org 10172 in Acute Stroke Treatment (TOAST) criteria. The means of oxidized low-density lipoprotein and interleukin-6 levels of patients with acute ischemic stroke were higher than controls (P < .01, P < .05). Mean oxidized low-density lipoprotein level was higher in the large-vessel disease group than in the small-vessel disease group (P < .01). The mean of inteleukin-6 levels was higher in the small-vessel disease group (P < .01). The results of the present study showed that oxidative stress promotes large-vessel disease rather than small-vessel disease stroke, and inflammation may play important an role in the development of small-vessel disease stroke.en_US
dc.identifier.doi10.1177/0003319707304134
dc.identifier.endpage229en_US
dc.identifier.issn0003-3197
dc.identifier.issue2en_US
dc.identifier.pmid18388043en_US
dc.identifier.scopus2-s2.0-42049098909en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage224en_US
dc.identifier.urihttps://doi.org/10.1177/0003319707304134
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21986
dc.identifier.volume59en_US
dc.identifier.wosWOS:000255137200014en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofAngiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIschemic Strokeen_US
dc.subjectOxidized Low-Density Lipoproteinen_US
dc.subjectInterleukin-6en_US
dc.subjectAtherosclerosisen_US
dc.subjectProinflammatory Cytokinesen_US
dc.subjectAdhesion Moleculesen_US
dc.subjectLdlen_US
dc.subjectInflammationen_US
dc.subjectExpressionen_US
dc.subjectDiseaseen_US
dc.subjectMarkeren_US
dc.subjectAtherosclerosisen_US
dc.subjectActivationen_US
dc.subjectInfarctionen_US
dc.titleThe roles of oxidized low-density lipoprotein and interleukin-6 levels in acute atherothrombotic and lacunar ischemic strokeen_US
dc.typeArticleen_US

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