Effectiveness of preoperative plasmapheresis in a pregnancy complicated by hyperthyroidism and anti-thyroid drug-associated angioedema

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dc.authoridKirkizlar, Onur/0000-0001-7523-8599
dc.authoridAKPINAR, SEVAL/0000-0002-6961-8971
dc.authorwosidKirkizlar, Onur/W-9594-2018
dc.authorwosidAKPINAR, SEVAL/HKD-9650-2023
dc.contributor.authorBilir, B. Ekiz
dc.contributor.authorAtile, N. Soysal
dc.contributor.authorKirkizlar, O.
dc.contributor.authorKomurcu, Y.
dc.contributor.authorAkpinar, S.
dc.contributor.authorSezer, A.
dc.contributor.authorDemir, M.
dc.date.accessioned2024-06-12T10:51:41Z
dc.date.available2024-06-12T10:51:41Z
dc.date.issued2013
dc.departmentTrakya Üniversitesien_US
dc.description.abstractHyperthyroidism is not a rare entity in pregnancy and 85% of these cases attributed to Graves' disease (GD). There is no therapeutic modality for GD considered as totally safe in pregnancy. Fetal and neonatal risks of maternal hyperthyroid disease are related to the hyperthyroidism itself and/or to the medical treatment of the disease. There are no data supporting an association between congenital anomalies in the fetus and propylthiouracil (PTU). Hepatotoxicity, cytopenias - especially agranulocytosis and quite rarely, angioedema, may be seen as side effects of PTU. In this case report, we examine an instance of Graves' hyperthyroidism diagnosed during pregnancy. In this case, a serious side effect during antithyroid drug usage was encountered, eventually resulting in surgery in the second trimester. This intervention was assisted by the use of plasmapheresis to obtain rapid normalization of serum thyroid hormone levels.en_US
dc.identifier.doi10.3109/09513590.2012.754871
dc.identifier.endpage510en_US
dc.identifier.issn0951-3590
dc.identifier.issn1473-0766
dc.identifier.issue5en_US
dc.identifier.pmid23383744en_US
dc.identifier.scopus2-s2.0-84875868523en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage508en_US
dc.identifier.urihttps://doi.org/10.3109/09513590.2012.754871
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18457
dc.identifier.volume29en_US
dc.identifier.wosWOS:000316956300024en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofGynecological Endocrinologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAngioedemaen_US
dc.subjectHyperthyroidismen_US
dc.subjectPlasmapheresisen_US
dc.subjectPregnancyen_US
dc.subjectTherapeutic Plasmapheresisen_US
dc.titleEffectiveness of preoperative plasmapheresis in a pregnancy complicated by hyperthyroidism and anti-thyroid drug-associated angioedemaen_US
dc.typeArticleen_US

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