Monocyte-to-HDL-cholesterol ratio is associated with Ascending Aorta Dilatation in Patients with Bicuspid Aortic Valve
Küçük Resim Yok
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Makerere Univ, Fac Med
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: The importance of monocyte count-to-HDL-cholesterol ratio (MHR) in cardio-vascular diseases has been shown in various studies. Ascending aortic dilatation (AAD) is a common complication in the patients with bicuspid aortic valve. In this study, we aimed to investigate the relationship between MHR and the presence of aortic dilatation in the patients with bicuspid aortic valve. Methods: The study population included totally 347 patients with bicuspid aortic valve.169 patients with aortic dilatation (ascending aorta diameter >= 4.0 cm) and 178 patients with no aortic dilatation. Echocardiographic and laboratory measurement was done and compared between groups. Results: The mean age of the participants was 44.7 +/- 15.4 years and average ascending aorta diameter was 3.2 +/- 0.3 cm in dilatation negative group and 4.4 +/- 0.4 cm in positive group. MHR was significantly increased in in patients with aortic dilatation. MHR and uric acid level was independently associated with the presence of aortic dilatation in the patients with bicuspid aortic valve. Conclusion: We found a significant relationship between MHR and aortic dilatation in the patients with bicuspid aortic valve.
Açıklama
Anahtar Kelimeler
Bicuspid Aorta, Aorta Aneurysm, Monocyte HDL Ratio, Inflammation, Density-Lipoprotein-Cholesterol, Uric-Acid Levels, Hypertensive Patients, Stenosis, Disease, Echocardiography, Complications, Binding, Adults, Flow
Kaynak
African Health Sciences
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
21
Sayı
1