Prognostic Significance of Critical Patients' Platelet Indexes in Mixed Type Critical Care Unit

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dc.authoridinal, volkan/0000-0003-2649-104X
dc.authoridEfe, Serdar/0000-0002-1229-0602
dc.authoridefe, serdar/0000-0002-1229-0602;
dc.authorwosidinal, volkan/A-6069-2018
dc.authorwosidEfe, Serdar/O-9237-2019
dc.authorwosidefe, serdar/R-8350-2017
dc.authorwosidEfe, Serdar/JAN-4839-2023
dc.contributor.authorEfe, Serdar
dc.contributor.authorAsker, Ismail
dc.contributor.authorInal, Volkan
dc.date.accessioned2024-06-12T11:12:28Z
dc.date.available2024-06-12T11:12:28Z
dc.date.issued2019
dc.departmentTrakya Üniversitesien_US
dc.description.abstractIntroduction: Thrombocyte indexes (TIN) are biological markers of thrombocyte morphology and function. In critical patients, few studies evaluated TIN relation with disease severity and prognosis. Aim: In this study, we objected to evaluate TIN as a routine feasible parameter at respect of clinical significance to predicting mortality, even though thrombocyte count and functions were prone to alter by variable conditions of critical care unit patients. Materials and methods: Data of 314 patients those with objected parameters out of 347 retrospectively evaluated for TIN relation with clinical surveillance and demographics, in a ten bed capacity mixed-type tertiary CCU in between Jan 1st - 31st Dec 2016. Results: Patients', 194 male (62%), mean age was 62.7 +/- 16.9 (19-86) and APACHE II score was 18.9 +/- 8.5, mean length of stay (LOS) was 9.1 (1-182) days and with 43% mortality. The mean thrombocyte volume (MPV) and dispersion width (PDW) indexes were both correlated each other and positively with disease severity, on the other hand negatively with thrombocyte count. The higher plateletcrit (PCT) levels otherwise lower MPV and PDW were found in males, and also showed relatively lower mortality rates (37.6%<44.1%) (p<0.01). Increrased PDW levels and lower thrombocyte counts were related to higher mortality, in addition to this, PCT<0.17 levels showed 2x higher mortality risk compared to PCT>0.32. Both PDW/PLT and PDW/PCT ratios related to mortality too (p<0.001, p<0.001), otherwise with relatively lower coefficients (r: 0,11, r: 0,10). Conclusion: TIN in mixed type CCUs was assumed as PDW and PCT could be included to disease severity scoring system prognostic biomarkers, like thrombocyte counts.en_US
dc.identifier.doi10.33381/dcbybd.2019.1877
dc.identifier.endpage17en_US
dc.identifier.issn1309-1689
dc.identifier.issn1309-6222
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85068618195en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage13en_US
dc.identifier.trdizinid322976en_US
dc.identifier.urihttps://doi.org/10.33381/dcbybd.2019.1877
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/322976
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23184
dc.identifier.volume10en_US
dc.identifier.wosWOS:000500542600003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherTurkish Soc Medical & Surgical Intensive Care Medicineen_US
dc.relation.ispartofJournal Of Medical And Surgical Intensive Care Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPlatelet Indexesen_US
dc.subjectMean Platelet Volumeen_US
dc.subjectPlatelet Dispersion Widthen_US
dc.subjectPlatelecriten_US
dc.subjectDistribution Widthen_US
dc.subjectVolumeen_US
dc.subjectSeverityen_US
dc.subjectRatioen_US
dc.titlePrognostic Significance of Critical Patients' Platelet Indexes in Mixed Type Critical Care Uniten_US
dc.typeArticleen_US

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