ARE THE DISINFECTANTS USED IN HOSPITALS ALSO EFFECTIVE ON BACTERIA THAT CAUSE NOSOCOMIAL INFECTIONS?: A UNIVERSITY HOSPITAL INVESTIGATION
Küçük Resim Yok
Tarih
2022
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
University of Ankara
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: Determining the disinfectant activity regularly will result in proper disinfection. In our study, it was aimed to determine the efficacy, effective concentrations and durations of some disinfectants used in Trakya University Hospital against nosocomial bacteria isolated from the same center. Material and Method: MRSA, VRE, Klebsiella pneumoniae and Acinetobacter baumannii isolates and 10 different disinfectants supplied from the same center were included in the study. Susceptibility tests and Qualitative Suspension Test were applied through the guidelines of CLSI M100-S25 and TS/EN/1040:2005 (formerly TS/EN/1040:1999), respectively. Qualitative Suspension Test was modified by using D/E Neutralizing Broth instead of adding a neutralizing agent. Result and Discussion: As a result, it was determined that all isolates were susceptible in the application conditions. However, peracetic acid, sodium dichloroisocyanurate, non-ionic active agent and sodium hypochlorite containing disinfectants being used in the hospital were not effective against some strains isolated from the hospital. Even the resistance of a single isolate to the application conditions of a disinfectant may lead to selection and proliferation of the strains and this may cause hospital infections. Our results might provide a reference to indicate the importance of selecting appropriate disinfectants and appropriate conditions for cleaning and disinfection in hospitals. © 2022 University of Ankara. All rights reserved.
Açıklama
Anahtar Kelimeler
Acinetobacter Baumannii; Esbl; Klebsiella Pneumoniae; Mrsa; Qualitative Suspension Test; Vre, 2 Propanol; Alcohol; Ampicillin; Anionic Surfactant; Benzalkonium Chloride; Benzyl Alcohol; Bovine Serum Albumin; Calcium Carbonate; Cationic Surfactant; Cefotaxime; Cefoxitin; Ceftazidime; Chlorhexidine Gluconate; Ciprofloxacin; Clavulanic Acid; Disinfectant Agent; Distilled Water; Enzyme; Extended Spectrum Beta Lactamase; Gentamicin; Glutaraldehyde; Hand Sanitizer; Hypochlorite; Hypochlorite Sodium; Imipenem; Meropenem; Peracetic Acid; Povidone Iodine; Propionate Sodium; Propionic Acid; Quaternary Ammonium Derivative; Sodium Carbonate; Troclosene; Vancomycin; Acinetobacter Baumannii; Antibiotic Sensitivity; Article; Bacterium Isolation; Broth Dilution; Clinical Effectiveness; Controlled Study; Devices; Disinfection; Disk Diffusion; Effective Concentration; Hospital; Hospital Infection; Klebsiella Pneumoniae; Methicillin Resistant Staphylococcus Aureus; Nonhuman; Practice Guideline; Qualitative Suspension Test; Treatment Duration; University Hospital; Vancomycin Resistant Enterococcus; Water Hardness
Kaynak
Ankara Universitesi Eczacilik Fakultesi Dergisi
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
46
Sayı
1
