Hypothesis: temperature stress and blood viscosity affects the leukocyte flexibility, coagulation, intracranial hypertension, and hemodynamics

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dc.contributor.authorCinar, Yildirim
dc.contributor.authorKosku, Nilufer
dc.date.accessioned2024-06-12T11:16:09Z
dc.date.available2024-06-12T11:16:09Z
dc.date.issued2011
dc.departmentTrakya Üniversitesien_US
dc.descriptionInternational Conference on Life Science and Technology (ICLST 2011) -- JAN 07-09, 2011 -- Mumbai, INDIAen_US
dc.description.abstractThe aim of the study was to investigating of the relationships between temperature, flexibility of leukocytes, and viscosity, flow rate, pressure, and coagulation of blood. Method: Healthy 37 cases were chosen with Simple Random Sampling Method. Heparinized bloods were collected and then leukocyte suspensions were separated with the clinical centrifuge. The viscosity and flexibility of the samples were measured at 25 degrees C, 37 degrees C, and 39 degrees C with capillary tube viscometer. Hemodynamical parameters were calculated using Poiseuille's equation. The Pillai's Trace test was used for the statistical evaluation. Results: When the temperature of blood decreased from 37 degrees C to 25 degrees C, the viscosity of blood increased from 11.70+/-0.4s to 15.10+/-0.6s as 29.05% (p<0.0001). With a temperature increase from 37 degrees C to 39 degrees C, the viscosity of blood decreased from 11.70+/-0.4s to 10.12+/-0.35s as 13.50% (p<0.0001). Discussion: The data and flow charts of the study show that increase of blood viscosity due to decreased temperature could be related with decreased intracranial pressure, decreased blood flow rate, stasis, vasodilatation, headache, increased local concentration of coagulation factors that facilitate amplification of coagulation and formation of thrombus. Results of the study could provide capacities for distinct diagnosis, selective therapies, and regulation of cerebral blood flow; prevention from stasis, thrombus formation and bleeding; explanations of anemia related intracranial hypertension and headache; and it constitute a new expanded scalar base within mathematical accuracy for future investigations.en_US
dc.description.sponsorshipAsia Pacific Chem Biol & Environm Engn Soc,IEEEen_US
dc.identifier.endpage126en_US
dc.identifier.isbn978-981-08-8715-5
dc.identifier.issn2010-4618
dc.identifier.startpage120en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24191
dc.identifier.volume3en_US
dc.identifier.wosWOS:000392766300031en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherInt Assoc Computer Science & Information Technology Press-Iacsit Pressen_US
dc.relation.ispartofLife Science And Technologyen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTemperatureen_US
dc.subjectBlood Viscosityen_US
dc.subjectHeadacheen_US
dc.subjectCoagulationen_US
dc.subjectLeukocyte Flexibilityen_US
dc.subjectBlood Flow Rateen_US
dc.subjectHemodynamicsen_US
dc.subjectHematocriten_US
dc.subjectFlowen_US
dc.subjectHeadacheen_US
dc.subjectPressureen_US
dc.subjectVelocityen_US
dc.titleHypothesis: temperature stress and blood viscosity affects the leukocyte flexibility, coagulation, intracranial hypertension, and hemodynamicsen_US
dc.typeConference Objecten_US

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