Soluble CD40 ligand and prolactin levels in migraine patients during interictal period

Basit Öğe Kaydı
dc.authoridGULDIKEN, Baburhan/0000-0002-9006-1880
dc.contributor.authorGuldiken, Sibel
dc.contributor.authorGuldiken, Baburhan
dc.contributor.authorDemir, Muzaffer
dc.contributor.authorKabayel, Levent
dc.contributor.authorOzkan, Hulya
dc.contributor.authorTurgut, Nilda
dc.contributor.authorHunkar, Remziye
dc.date.accessioned2024-06-12T11:08:34Z
dc.date.available2024-06-12T11:08:34Z
dc.date.issued2011
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThe relationship of migraine with cardiovascular diseases has been clarified by many studies, and currently, migraine is suggested to be a systematic vasculopathy. Inflammation, thrombosis and impaired vascular reactivity are the underlying pathophysiological mechanisms of the vasculopathy. In the present study, we aimed to investigate the relationship between prolactin levels and subclinical atherosclerosis risk factors such as soluble CD40 ligand (sCD40L) and high-sensitivity CRP (hsCRP) in migraine patients during interictal period. Fifty female migraine patients and age-matched 25 female control cases were enrolled in the study. Migraine diagnosis was settled according to the ICHD-II diagnostic criteria. A questionnaire was completed about the existence of vascular risk factors. Serum samples were used to measure sCD40L, hsCRP and prolactin levels. No difference was found between the prolactin levels of the migraine patients and the controls. The sCD40L levels were significantly higher in migraine patients (p<0.001). High-sensitivity CRP levels showed no difference between the groups. There was no correlation between prolactin, sCD40L, and hs-CRP levels in migraine patients. We consider that the migraine patients are prone to subclinical atherosclerosis, but this tendency is independent of prolactin levels.en_US
dc.identifier.doi10.1007/s10194-011-0306-8
dc.identifier.endpage360en_US
dc.identifier.issn1129-2369
dc.identifier.issn1129-2377
dc.identifier.issue3en_US
dc.identifier.pmid21331754en_US
dc.identifier.scopus2-s2.0-79958174562en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage355en_US
dc.identifier.urihttps://doi.org/10.1007/s10194-011-0306-8
dc.identifier.urihttps://hdl.handle.net/20.500.14551/22482
dc.identifier.volume12en_US
dc.identifier.wosWOS:000292908100014en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBmcen_US
dc.relation.ispartofJournal Of Headache And Painen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMigraineen_US
dc.subjectProlactinen_US
dc.subjectScd40len_US
dc.subjectSubclinical Atherosclerosisen_US
dc.subjectC-Reactive Proteinen_US
dc.subjectCardiovascular Risken_US
dc.subjectUp-Regulationen_US
dc.subjectSensitivityen_US
dc.subjectDiseaseen_US
dc.subjectCellsen_US
dc.subjectAtherosclerosisen_US
dc.subjectInvolvementen_US
dc.subjectActivationen_US
dc.subjectExpressionen_US
dc.titleSoluble CD40 ligand and prolactin levels in migraine patients during interictal perioden_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu