Assessment of disease activity in large-vessel vasculitis: Results of an international delphi exercise

dc.authorscopusid22633521000
dc.authorscopusid55872112400
dc.authorscopusid57209188029
dc.authorscopusid6508102640
dc.authorscopusid55981133400
dc.authorscopusid7401856702
dc.authorscopusid9243496300
dc.contributor.authorAydin S.Z.
dc.contributor.authorDireskeneli H.
dc.contributor.authorMerkel P.A.
dc.contributor.authorToloza S.
dc.contributor.authorBlockmans D.
dc.contributor.authorSato E.I.
dc.contributor.authorDe Souza A.W.S.
dc.date.accessioned2024-06-12T10:26:10Z
dc.date.available2024-06-12T10:26:10Z
dc.date.issued2017
dc.description.abstractObjective. To arrive at consensus for candidate outcomes for disease activity assessment in largevessel vasculitis (LVV) in clinical trials. Methods.A Delphi survey including 99 items was circulated among international experts for 3 rounds. Results. Fifty-seven items were accepted for both giant cell arteritis and Takayasu arteritis. Sixty-seven percent of experts voted to have a common approach for both diseases with additional disease-specific items such as weight loss, scalp tenderness/necrosis, morning stiffness, dizziness, visual symptoms, and imaging. Conclusion. This study highlights similarities and differences in experts' perspectives for assessing clinical activity in LVV and may guide a consensus-driven core set of validated outcomes. Copyright © 2017. All rights reserved.en_US
dc.description.sponsorshipNational Institute of Arthritis and Musculoskeletal and Skin Diseases, NIAMS: U01 AR51874 04, U54AR057319; National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIAMS; National Center for Research Resources, NCRR: U54 RR019497; National Center for Research Resources, NCRR; Vasculitis Clinical Research Consortium, VCRCen_US
dc.description.sponsorshipSponsored by the Vasculitis Clinical Research Consortium, which has received support from the US National Institute of Arthritis and Musculoskeletal and Skin Diseases (U54 AR057319 and U01 AR51874 04), the National Center for Research Resources (U54 RR019497), and the Office of Rare Diseases Research. Additional support for the work of the OMERACT Vasculitis Working Group was received through a Patient-Centered Outcomes Research Institute Pilot Project Grant. S.Z. Aydin, MD, Associate Professor, Division of Rheumatology, The Ottawa Hospital Research Institute, University of Ottawa; H. Direskeneli, MD, Professor of Rheumatology, Division of Rheumatology, Marmara University Faculty of Medicine; P.A. Merkel, MD, MPH, Professor of Medicine and Epidemiology, Division of Rheumatology, and Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania. Address correspondence to Dr. P.A. Merkel, Section of Rheumatology, University of Pennsylvania, White Building, 5th Floor Penn, 3400 Spruce St., Philadelphia, Pennsylvania 19104, USA. E-mail: pmerkel@upenn.edu Accepted for publication June 3, 2017.en_US
dc.identifier.doi10.3899/jrheum.161269
dc.identifier.endpage1932en_US
dc.identifier.issn0315-162X
dc.identifier.issue12en_US
dc.identifier.pmid28864648en_US
dc.identifier.scopus2-s2.0-85037094161en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1928en_US
dc.identifier.urihttps://doi.org/10.3899/jrheum.161269
dc.identifier.urihttps://hdl.handle.net/20.500.14551/16684
dc.identifier.volume44en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherJournal of Rheumatologyen_US
dc.relation.ispartofJournal of Rheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGiant Cell Arteritis; Large Vessel; Outcomes; Takayasu Arteritis; Vasculitisen_US
dc.subjectAortic Arch Syndrome; Article; Blood Vessel Diameter; Clinical Outcome; Consensus; Delphi Study; Disease Activity; Dizziness; Giant Cell Arteritis; Health Survey; Human; International Cooperation; Large Vessel Vasculitis; Medical Expert; Musculoskeletal Stiffness; Outcome Assessment; Priority Journal; Skin Necrosis; Vasculitis; Visual Disorder; Weight Reduction; Aortic Arch Syndrome; Giant Cell Arteritis; Severity Of Illness Index; Delphi Technique; Giant Cell Arteritis; Humans; Severity Of Illness Index; Takayasu Arteritisen_US
dc.titleAssessment of disease activity in large-vessel vasculitis: Results of an international delphi exerciseen_US
dc.typeArticleen_US

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