Investigation of Antimicrobial and Antitubercular Activities of Some Hydrazone DerivedCompounds

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dc.contributor.authorEvranos-Aksöz, Begüm
dc.contributor.authorOnurdağ, Fatma Kaynak
dc.contributor.authorAksöz, Erkan
dc.contributor.authorÖzgacar, Selda Özgen
dc.date.accessioned2024-06-12T10:04:17Z
dc.date.available2024-06-12T10:04:17Z
dc.date.issued2020
dc.departmentTrakya Üniversitesien_US
dc.description.abstractAseriesofhydrazonederivativesweresynthesizedtoinvestigate antifungal,antimicrobialandantitubercularactivities.Theseactivitieswere investigatedagainst Escherichiacoli, Escherichiacoli isolate, Pseudomonas aeruginosa, Pseudomonas aeruginosaisolate (resistant to gentamicin), Staphylococcus aureus, Staphylococcus aureus isolate (MRSA), Enterococcusfaecalis, Enterococcusfaecalis isolate(VRE), Candidaalbicans, Candidakrusei andMycobacteriumtuberculosis. Among the synthesized compounds B23had the best activity against Candida albicanswith 16 ?g/mL MIC value and B24had the best activity against Staphylococcus aureus isolate (MRSA) with 16 ?g/mL MIC value. The most effective compound against Mycobacteriumtuberculosis is found to be E9 with 32 ?g/mL MIC value, achalcone derivative. However, all compounds were determined as ineffective against Escherichia coli and Escherichia coli isolate.en_US
dc.identifier.doi10.19113/sdufenbed.672554
dc.identifier.endpage200en_US
dc.identifier.issn1300-7688
dc.identifier.issn1308-6529
dc.identifier.issue1en_US
dc.identifier.startpage196en_US
dc.identifier.trdizinid376625en_US]
dc.identifier.urihttps://doi.org/10.19113/sdufenbed.672554
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/376625
dc.identifier.urihttps://hdl.handle.net/20.500.14551/12734
dc.identifier.volume24en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofSüleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleInvestigation of Antimicrobial and Antitubercular Activities of Some Hydrazone DerivedCompoundsen_US
dc.typeArticleen_US

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