Lupus pernio in sarcoidosis -: Clinical features and treatment outcomes of 14 patients

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dc.contributor.authorYanardag, H
dc.contributor.authorPamuk, ÖN
dc.contributor.authorPamuk, GE
dc.date.accessioned2024-06-12T11:13:54Z
dc.date.available2024-06-12T11:13:54Z
dc.date.issued2003
dc.departmentTrakya Üniversitesien_US
dc.description.abstractLupus perio, (LP) is the most characteristic skin lesion of sarcoidosis. In this study, we retrospectively evaluated the clinical features of sarcoidosis patients with diagnosed LP at our center. Of 516 sarcoidosis patients diagnosed within a 36-year period, 14 (2.7%) had skin lesions that were clinically and histologically diagnosed as LP. Thirteen of our LP patients were females, and one was a male (mean age: 46.3, range: 24-67). In 2 sarcoidosis patients, the initial presentation of the disease was LP. When the LP patients were compared with other sarcoidosis patients, there were more fe- males, and the frequency of extrapidnionary involvement and the number of patients with advanced stage disease were higher (P <0.001). Oral and/or intralesional steroid therapy was the preferred treatment modality in all our patients and led to either recovery or regression in most patients with IP. As our study was an uncontrolled, retrospective one with few patients, it is difficult to say whether steroids are effective. LP runs a chronic course and spontaneous remission of lesions of more than 2 years' duration is quite rare. Because of the unwanted side effects of steroids, the efficacy of new treatment modalities should be tested especially in sarcoidosis patients with only skin involvement.en_US
dc.identifier.doi10.1097/01.RHU.0000062509.01658.d1
dc.identifier.endpage76en_US
dc.identifier.issn1076-1608
dc.identifier.issn1536-7355
dc.identifier.issue2en_US
dc.identifier.pmid17041433en_US
dc.identifier.startpage72en_US
dc.identifier.urihttps://doi.org/10.1097/01.RHU.0000062509.01658.d1
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23717
dc.identifier.volume9en_US
dc.identifier.wosWOS:000187660400002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofJcr-Journal Of Clinical Rheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSarcoidosisen_US
dc.subjectLupus Pernioen_US
dc.subjectCutaneous Involvementen_US
dc.subjectCorticosteroidsen_US
dc.subjectCutaneous Sarcoidosisen_US
dc.subjectErythematosusen_US
dc.titleLupus pernio in sarcoidosis -: Clinical features and treatment outcomes of 14 patientsen_US
dc.typeArticleen_US

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