Caudal ropivacaine and neostiginine in pediatric surgery

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dc.contributor.authorTuran, A
dc.contributor.authorMemis, D
dc.contributor.authorBasaran, ÜN
dc.contributor.authorKaramanlioglu, B
dc.contributor.authorSüt, N
dc.date.accessioned2024-06-12T11:19:38Z
dc.date.available2024-06-12T11:19:38Z
dc.date.issued2003
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground: Neostigmine has been added to local anesthetics for different nerve blocks. This study was conducted to evaluate effects of neostigmine when added to ropivacaine for caudal anesthesia. Methods: We studied children, aged 1-5 yr, undergoing inguinal hernia and hypospadias surgery. After standard induction of anesthesia, Group I received 0.2% ropivacaine 0.5 ml/kg and Group II received 0.2% ropivacaine 0.5 ml/kg with 2 ml/kg neostigmine via the caudal route. Heart rate, mean arterial pressure, and pulse oximetry were recorded before induction, after induction, and then every 10 min after caudal anesthesia. Hemodynamic, Toddler-Preschooler Postoperative Pain Scale pain score, and sedation score values were recorded 30 min after extubation and at hours 2, 4, 6, 12, and 24. A pain score greater than 3/10 resulted in administration of rectal paracetamol. Results: There were no differences between the groups in demographic and hemodynamic data, duration of surgery and anesthesia, time to extubation, or sedation scores. The pain scores were significantly lower in Group II at 6 and 12 h (P < 0.05). Time to first analgesic requirement was statistically prolonged in Group II (19.2 +/- 5.5h) when compared with Group 1 (7.1 +/- 5.7 h) (P < 0.05). Total analgesic consumption was statistically larger in Group I (174 +/- 96 mg) when compared with Group II (80 +/- 85.5 mg) (P < 0.05). The incidence of vomiting (3 patients in Group II and 1 patient in Group I) was not statistically significantly different. Conclusions: The authors found that a single caudal injection of neostigmine when added to ropivacaine offers an advantage over ropivacaine alone for postoperative pain relief in children undergoing genitourinary surgery.en_US
dc.identifier.doi10.1097/00000542-200303000-00021
dc.identifier.endpage722en_US
dc.identifier.issn0003-3022
dc.identifier.issue3en_US
dc.identifier.pmid12606917en_US
dc.identifier.scopus2-s2.0-0037370349en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage719en_US
dc.identifier.urihttps://doi.org/10.1097/00000542-200303000-00021
dc.identifier.urihttps://hdl.handle.net/20.500.14551/25286
dc.identifier.volume98en_US
dc.identifier.wosWOS:000181290800020en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofAnesthesiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPostoperative Analgesiaen_US
dc.subjectIntrathecal Neostigmineen_US
dc.subjectEpidural Neostigmineen_US
dc.subjectBupivacaineen_US
dc.subjectChildrenen_US
dc.subjectMorphineen_US
dc.subjectAnesthesiaen_US
dc.subjectClonidineen_US
dc.subjectBlockadeen_US
dc.subjectKetamineen_US
dc.titleCaudal ropivacaine and neostiginine in pediatric surgeryen_US
dc.typeArticleen_US

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