Evaluation of clinical activity and functional impairment in smokers with Ankylosing spondylitis

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dc.contributor.authorKaan, U
dc.contributor.authorFerda, Ö
dc.date.accessioned2024-06-12T10:51:45Z
dc.date.available2024-06-12T10:51:45Z
dc.date.issued2005
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground: Ankylosing spondylitis (AS), a rheumatic disease, incapacitates human beings during the most productive stage of their lives, causes functional disturbances, and thus affects both patients and their relatives. Disease activity, functional impairment, and efficacy of treatment are affected by various environmental and genetic factors, one of which is smoking. We investigated smoking's effect on clinical activity and functional impairment in AS. Patients and methods: Forty-eight patients with back pain and limited movements, diagnosed with AS based on clinical, radiological, and laboratory examinations and referred to the Trakya University School of Medicine Physical Medicine and Rehabilitation Department in Turkey were included in this study. Disease activity was evaluated with the Bath Ankylosing Spondylitis Disease Activity Index ( BASDAI) and functional impairment with the Bath Ankylosing Spondylitis Functional Index (BASFI). The Mann-Whitney U test was used to determine relationships between smoking and physical findings, laboratory results, and BASDAI and BASFI scores. Results: Twenty-four patients were smokers. They had significantly higher BASDAI and BASFI scores and significantly lower forced vital capacity values than nonsmokers (P = 0.000, P = 0.002, and P = 0.001, respectively) ( Mann-Whitney U test). Conclusion: Smoking is associated with poor clinical aspect and functional impairment in AS. The underlying mechanism can be the physical incapacity caused by smoking.en_US
dc.identifier.doi10.1007/s00296-004-0451-3
dc.identifier.endpage360en_US
dc.identifier.issn0172-8172
dc.identifier.issn1437-160X
dc.identifier.issue5en_US
dc.identifier.pmid14991231en_US
dc.identifier.scopus2-s2.0-21644472085en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage357en_US
dc.identifier.urihttps://doi.org/10.1007/s00296-004-0451-3
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18477
dc.identifier.volume25en_US
dc.identifier.wosWOS:000229906100008en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofRheumatology Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnkylosing Spondylitisen_US
dc.subjectBASDAIen_US
dc.subjectBASFIen_US
dc.subjectSmokingen_US
dc.subjectDisease-Activityen_US
dc.subjectCigarette-Smokingen_US
dc.subjectIndexen_US
dc.subjectAssociationen_US
dc.subjectPredictorsen_US
dc.subjectDisabilityen_US
dc.subjectSeten_US
dc.titleEvaluation of clinical activity and functional impairment in smokers with Ankylosing spondylitisen_US
dc.typeArticleen_US

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