An analysis of overall survival in patients who have undergone lung metastasectomy operations for lung metastases of colorectal cancers and malignancies other than colorectal cancer
Küçük Resim Yok
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Kuwait Medical Assoc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: To compare the survival and factors affecting survival between patient groups with primary colorectal cancers and malignancies other than colorectal cancer, who underwent curative pulmonary metastasectomy Design: Retrospective study Setting: Trakya University School of Medicine, Edirne, Turkey Subjects: Forty-four cases who underwent curative metastasectomy in our clinic between January 2006 and August 2015 Interventions: Primary colorectal cancers (Group 1 = 14 cases), malignancies other than colorectal cancer (Group 2 = 30 cases) Main outcome measure(s): Age, gender, type of primary malignity, disease-free survival, adjuvant therapy, number of radiological nodules, number and type of operations, number and site of nodules resected, presence of relapse, and mean survival Results: Two cases (4.7%) underwent lobectomy, and a total of 123 nodules were excised in 38 cases (86.3%) using thoracotomy and in four cases (9%) using video thoracoscopic surgery. The median survival value was 33 +/- 5.4 months (range:22.2 - 43.7 months) in Group 1, and 28 +/- 6.8 months (range:14.5 - 41.4 months) in Group 2; the cumulative value was 33 +/- 3.7 months (range:25.6 - 40.3 months). Survival did not differ significantly between the groups (p=0.738). Age (p=0.81), gender (p=0.35), disease-free survival (p=0.24), number of metastatic nodules (p=0.60), presence of synchronous-metachronous tumor (p=0.94), adjuvant chemotherapy (p=0.96), adjuvant radiotherapy (p=0.86), and relapse of disease (p=0.07) were not significantly correlated with survival. Conclusion: Survival and factors that affected survival did not differ significantly between the two groups that underwent metastasectomy. It was indicated that the primary tumor is not an effective factor in the selection of patients who would undergo metastasectomy.
Açıklama
Anahtar Kelimeler
Colorectal Tumors, Lung Tumors, Metastasis, Long-Term Survival, Surgical Resection
Kaynak
Kuwait Medical Journal
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
51
Sayı
4
