Immunohistochemical distribution of glucagon -, insulin -, somatostatin -, gastrin-, and serotonin-containing cells in the pancreas of the Van cat

dc.authoridYörük, Mecit/0000-0001-6820-8105
dc.authoridKARACA, Turan/0000-0002-2500-7781
dc.authoridKara, Adem/0000-0002-5766-6116
dc.authoridUslu, Sema/0000-0002-2239-7841
dc.authorwosidYörük, Mecit/AAG-4710-2019
dc.authorwosidKARACA, Turan/ABD-6669-2020
dc.authorwosidKara, Adem/J-4911-2013
dc.authorwosidSimsek, Nejdet/B-4040-2008
dc.authorwosidUslu, Sema/JVP-3565-2024
dc.contributor.authorKaraca, Turan
dc.contributor.authorKara, Adem
dc.contributor.authorSimsek, Nejdet
dc.contributor.authorUslu, Sema
dc.contributor.authorTekiner, Deniz
dc.contributor.authorYoruk, Mecit
dc.date.accessioned2024-06-12T11:00:24Z
dc.date.available2024-06-12T11:00:24Z
dc.date.issued2014
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThe regional distribution, relative frequency, and appearance of glucagon (A-cell)-, insulin (B-cell)-, somatostatin (D-cell)-, gastrin (G-cell)-, and serotonin (EC-cell)-secreting cells in the endocrine and exocrine pancreas of Van cats were examined using the immunohistochemistry method. Glucagon immunopositive A-cells were principally found in the central region of the islets of Langerhans, while insulin immunopositive B-cells were located in the periphery of the pancreatic islets. Moreover, several A- and B-cells were observed as only single cells or clusters of 2 to 3 immunopositive cells in the exocrine parenchyma and the pancreatic duct epithelium. Somatostatin and gastrin immunopositive reactivities were negligible in the peripheral regions of the pancreatic islets of Langerhans and in the exocrine parenchyma. However, serotonin-immunopositive EC-cells were observed in neither the endocrine islets nor any other sites of the tissue. The existence, regional distribution, and relative frequency of A-, B-, D-, G- and EC-cells in the pancreas of Van cats have been analyzed in this study for the first time. The immunopositivity and distribution of endocrine cells in the Van cat pancreas were determined to be partially different from those of other carnivorous species such as dogs and other cats.en_US
dc.identifier.doi10.3906/vet-1309-72
dc.identifier.endpage311en_US
dc.identifier.issn1300-0128
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84922833412en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage304en_US
dc.identifier.trdizinid165884en_US
dc.identifier.urihttps://doi.org/10.3906/vet-1309-72
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/165884
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20807
dc.identifier.volume38en_US
dc.identifier.wosWOS:000336891000013en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technological Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal Of Veterinary & Animal Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEndocrine Cellen_US
dc.subjectImmunohistochemistryen_US
dc.subjectLangerhans Isleten_US
dc.subjectVan Cat Pancreasen_US
dc.subjectIslet Architectureen_US
dc.subjectEndocrine-Cellsen_US
dc.subjectRaten_US
dc.subjectMorphometryen_US
dc.subjectNeogenesisen_US
dc.subjectSecretionen_US
dc.subjectMelatoninen_US
dc.subjectDamageen_US
dc.subjectMassen_US
dc.titleImmunohistochemical distribution of glucagon -, insulin -, somatostatin -, gastrin-, and serotonin-containing cells in the pancreas of the Van caten_US
dc.typeArticleen_US

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