Ventricular repolarization changes during thyrotropin releasing hormone test
Küçük Resim Yok
Tarih
2001
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Sci Ireland Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
We investigated the ventricular repolarization changes during thyrotropin-releasing hormone (TRH) test in 20 euthyroid healthy subjects. TSH elevation was observed in 14 subjects (age: 29 +/- 5 years). TSH increased at 20 min (baseline: 1.91 +/- 1.18 muU/ml vs. 20 min: 13.7 +/- 7.2 muU/ml, P < 0.0001) and slightly decreased at 40 min (baseline vs. 40 min: 11.6 6.7 muU/ml P < 0.0001). Many dispersions prolonged at 20 and 40 min (P < 0.05). At baseline, 20 and 40 min, positive linear correlations were observed between TSH levels and TTd and TTcd, These data shows: that ventricular repolarization and regional inhomogeneity of ventricular repolarization increase during the TRH test. Neural and receptor-mediated mechanisms on repolarization kinetics of myocardial cells may act on this effect. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
Açıklama
Anahtar Kelimeler
Thyroid Stimulating Hormone, QT Dispersion, Thyrotropin-Releasing Hormone Test, Ventricular Repolarization, Qt Interval Dispersion, Torsade-De-Pointes, Hypothyroidism
Kaynak
International Journal Of Cardiology
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
77
Sayı
2-3
