Metastatic squamous cell carcinoma of the skin in chronic myeloid leukaemia

Basit Öğe Kaydı
dc.authorwosidTurgut, Burhan/A-2517-2016
dc.contributor.authorPamuk, GE
dc.contributor.authorTurgut, B
dc.contributor.authorVurul, Ö
dc.contributor.authorDemir, M
dc.contributor.authorTek, M
dc.contributor.authorAltaner, S
dc.date.accessioned2024-06-12T11:03:28Z
dc.date.available2024-06-12T11:03:28Z
dc.date.issued2003
dc.departmentTrakya Üniversitesien_US
dc.description.abstractHydroxyurea is a ribonucleotide diphosphate reductase inhibitor used in the treatment of patients with myeloproliferative disorders. Hydroxyurea has some dermatological side-effects. It has recently been recognized that hydroxyurea can induce squamous cell and basal cell carcinomas of skin. We present the case of an elderly man with chronic myeloid leukaemia who was treated with hydroxyurea for 4 years, with good control of his disease. However, in addition to the appearance of various skin lesions and cutaneous squamous cell carcinoma after 3 years of therapy, he was found to have a metastatic squamous cell carcinoma after 4 years. Hydroxyurea was discontinued, and he underwent surgery and radiotherapy. The patient subsequently died of ventricular fibrillation. We present this case to draw attention to the association between hydroxyurea and secondary skin cancers and to emphasize the need for dermatological examination before and during the course of hydroxyurea therapy.en_US
dc.identifier.doi10.1046/j.1365-2257.2003.00534.x
dc.identifier.endpage331en_US
dc.identifier.issn0141-9854
dc.identifier.issue5en_US
dc.identifier.pmid12974726en_US
dc.identifier.scopus2-s2.0-0141528461en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage329en_US
dc.identifier.urihttps://doi.org/10.1046/j.1365-2257.2003.00534.x
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21676
dc.identifier.volume25en_US
dc.identifier.wosWOS:000185345000011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBlackwell Publishing Ltden_US
dc.relation.ispartofClinical And Laboratory Haematologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHydroxyureaen_US
dc.subjectChronic Myeloid Leukaemiaen_US
dc.subjectSquamous Cell Carcinomaen_US
dc.titleMetastatic squamous cell carcinoma of the skin in chronic myeloid leukaemiaen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu