Breast cancer in a woman with guillain–barré syndrome: A reminder to consider paraneoplastic neurological syndrome

Küçük Resim Yok

Tarih

2016

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Geriatrics Society

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

A72-year-old woman was referred to us for Guillain–Barré syndrome rehabilitation, during which her functional status improved (Hughes score 3–2, Functional Ambulation Classification Scale 2–4, Functional Independence Measure score 99–120). Despite her improvement, discharge was postponed because of a bloody discharge from her left nipple, which started 1 day before the last visit. The final diagnosis, after an excisional biopsy, was invasive ductal carcinoma with apocrine features. Guillain–Barré syndrome is an acute, rapidly progressing inflammatory polyneuropathy, with patients typically showing symmetrical, ascending weakness with a severe loss of reflexes. The current literature describes Guillain–Barré syndrome as a probable paraneoplastic neurological syndrome and cancer precursor. Guillain–Barré syndrome with this etiology, i.e., paraneoplastic neurological syndrome, may result from remote effects with immunological mechanisms that are not directly caused by the tumor or metastases infiltration. Guillain–Barré syndrome may develop as a paraneoplastic neurological syndrome, may be secondary to treatment, or may occur coincidentally with cancer. Because paraneoplastic neurological syndrome occurs at an early stage of cancer before metastasis, it is important to consider paraneoplastic neurological syndrome when evaluating Guillain–Barré syndrome patients. © 2016, Geriatrics Society. All rights reserved.

Açıklama

Anahtar Kelimeler

Breast Neoplasms; Guillain-Barré Syndrome; Paraneoplastic Syndromes, Immunoglobulin; Aged; Apocrine Gland; Article; Biopsy; Breast Cancer; Case Report; Electromyography; Female; Guillain Barre Syndrome; Human; Human Tissue; Mammography; Muscle Weakness; Nuclear Magnetic Resonance; Paget Nipple Disease; Paraneoplastic Neuropathy; Polyneuropathy; Reflex; Rehabilitation Care

Kaynak

Turk Geriatri Dergisi

WoS Q Değeri

Scopus Q Değeri

Q4

Cilt

19

Sayı

4

Künye