Obstructive Sleep Apnea and Cardiovascular Disease: Where Do We Stand?

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dc.authoridFIRAT, SELMA/0000-0002-1248-5602
dc.authoridPeker, Yüksel/0000-0001-9067-6538
dc.authoridYILDIRIR, Aylin/0000-0001-8750-5287
dc.authoridBAŞARAN, ÖZCAN/0000-0002-6384-6455
dc.authoridÇELİK, AHMET/0000-0002-9417-7610
dc.authoridDURSUNOGLU, Prof. Dr. Dursun/0000-0002-5232-7078
dc.authorwosidFIRAT, SELMA/A-8500-2018
dc.authorwosidBaşaran, Özcan/KIM-2166-2024
dc.authorwosidPeker, Yüksel/A-7550-2016
dc.authorwosidYILDIRIR, Aylin/A-4947-2018
dc.authorwosidBAŞARAN, ÖZCAN/H-4217-2019
dc.authorwosidaltay, servet/C-1387-2018
dc.authorwosidÇELİK, AHMET/AAA-6615-2021
dc.contributor.authorPeker, Yuksel
dc.contributor.authorAkdeniz, Bahri
dc.contributor.authorAltay, Servet
dc.contributor.authorBalcan, Baran
dc.contributor.authorBasaran, Ozcan
dc.contributor.authorBaysal, Erkan
dc.contributor.authorCelik, Ahmet
dc.date.accessioned2024-06-12T10:55:46Z
dc.date.available2024-06-12T10:55:46Z
dc.date.issued2023
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObstructive sleep apnea is common in adults with cardiovascular disease. Accumulating evidence suggests an association between obstructive sleep apnea and cardiovascular disease independent of the traditionally recognized cardiovascular disease risk factors. Observational studies indicate that obstructive sleep apnea is a risk factor for development of cardiovascular disease and that alleviation of obstructive events with positive airway pressure may improve cardiovascular disease outcomes. However, recent randomized controlled trials have not supported the beneficial effect of positive airway pressure in cardiac populations with concomitant obstructive sleep apnea. Some evidence suggests that the relationship between obstructive sleep apnea and traditionally recognized cardiovascular disease risk factors is bidirectional, suggesting that patients with cardiovascular disease may also develop obstructive sleep apnea and that efficient treatment of cardiovascular disease may improve obstructive sleep apnea. Recent data also indicate that the apnea-hypopnea index, which is commonly used as a diagnostic measure of obstructive sleep apnea severity, has limited value as a prognostic measure for cardiovascular disease outcomes. Novel markers of obstructive sleep apnea -associated hypoxic burden and cardiac autonomic response seem to be strong predictors of adverse cardiovascular disease outcomes and response to treatment of obstructive sleep apnea. This narrative review and position paper from the Turkish Collaboration of Sleep Apnea Cardiovascular Trialists aims to update the current evidence about the relationship between obstructive sleep apnea and cardiovascular disease and, consequently, raise awareness for health professionals who deal with cardiovascular and respiratory diseases to improve the ability to direct resources at patients most likely to benefit from treatment of obstructive sleep apnea and optimize treatment of the coexisting cardiovascular diseases. Moreover, the Turkish Collaboration of Sleep Apnea Cardiovascular Trialists aims to contribute to strengthening the efforts of the International Collaboration of Sleep Apnea Cardiovascular Trialists in this context.en_US
dc.identifier.doi10.14744/AnatolJCardiol.2023.3307
dc.identifier.endpage389en_US
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.issue7en_US
dc.identifier.pmid37284828en_US
dc.identifier.scopus2-s2.0-85163748027en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage375en_US
dc.identifier.trdizinid1187394en_US
dc.identifier.urihttps://doi.org/10.14744/AnatolJCardiol.2023.3307
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1187394
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19550
dc.identifier.volume27en_US
dc.identifier.wosWOS:001068578000004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKare Publen_US
dc.relation.ispartofAnatolian Journal Of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCardiovascular Diseaseen_US
dc.subjectCoronary Artery Diseaseen_US
dc.subjectHeart Failureen_US
dc.subjectHypertensionen_US
dc.subjectSleep Apneaen_US
dc.subjectPositive Airway Pressureen_US
dc.subjectCoronary-Artery-Diseaseen_US
dc.subjectNocturnal Blood-Pressureen_US
dc.subjectRostral Fluid Shiften_US
dc.subjectAmerican Academyen_US
dc.subjectHeart-Failureen_US
dc.subjectMandibular Advancementen_US
dc.subjectBerlin Questionnaireen_US
dc.subjectAtrial-Fibrillationen_US
dc.subjectDaytime Sleepinessen_US
dc.titleObstructive Sleep Apnea and Cardiovascular Disease: Where Do We Stand?en_US
dc.typeReview Articleen_US

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