Bile acid bearing poly (vinyl chloride) nanofibers by combination of CuAAC click chemistry and electrospinning process

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dc.authoridKARABULUT, H R Ferhat/0000-0002-9501-6296
dc.authoridAltinkok, Cagatay/0000-0002-0262-4154
dc.authoridACIK, Assoc. Prof. GOKHAN/0000-0002-9427-0508
dc.authoridtasdelen, mehmet atilla/0000-0002-7012-7029
dc.authorwosidKARABULUT, H R Ferhat/AAA-1402-2021
dc.authorwosidAltinkok, Cagatay/ABA-9208-2020
dc.authorwosidACIK, Assoc. Prof. GOKHAN/E-2922-2018
dc.authorwosidtasdelen, mehmet atilla/B-8338-2008
dc.contributor.authorAltinkok, Cagatay
dc.contributor.authorKarabulut, H. R. Ferhat
dc.contributor.authorTasdelen, M. Atilla
dc.contributor.authorAcik, Gokhan
dc.date.accessioned2024-06-12T10:54:29Z
dc.date.available2024-06-12T10:54:29Z
dc.date.issued2020
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThis study aims to deposit most common bile acids such as lithocholic acid (LCA) and chenodeoxycholic acid (CDCA) bearing poly (vinyl chloride) nanofiber (PVC-LCA and PVC-CDCA) coatings on glass slides surface using a combination method by employing copper (I)-catalyzed azide-alkyne cycloaddition 'click' reaction (CuAAC), followed by electrospinning process. The resulted nanofibers and their intermediates are characterized by spectroscopic (FT-(IRH)-H-1-NMR), thermal (TGA and DSC), wettability (WCA) and morphological (SEM) analyses. Many characterizations reveal that the bile acid functionalized PVC-LCA and PVC-CDCA are successfully achieved by CuAAC between azido-functional PVC (PVC-N-3) and alkyne end-functional LCA and CDCA (LCAA-lkyne and CDCA-Alkyne) and their nanofibers obtained by electrospinning show efficiently improved thermal behavior, hydrophilicity and morphological features compared to pristine PVC or their granule analogues. Furthermore, the SEM images indicate that the formation of nanoscale, uniform, cylindrical and smooth fibers without free beads. The changeable properties achieved are attributed to the presence of rigid steroid skeleton, triazole rings and free -OH groups on the final polymers. Hence, it is clear that this facile combination procedure is encouraging for scientists working on potential biomedical PVC applications.en_US
dc.description.sponsorshipTrakya University Research Fund [2018/278]en_US
dc.description.sponsorshipThe authors would like to thank Trakya University Research Fund for financial support (TUBAP Project No. 2018/278).en_US
dc.identifier.doi10.1016/j.mtcomm.2020.101425
dc.identifier.issn2352-4928
dc.identifier.scopus2-s2.0-85087590842en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1016/j.mtcomm.2020.101425
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19074
dc.identifier.volume25en_US
dc.identifier.wosWOS:000600999800007en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofMaterials Today Communicationsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBile Aciden_US
dc.subjectCopper (I)-Catalyzed Azide-Alkyne Cycloadditionen_US
dc.subjectElectrospinningen_US
dc.subjectPoly (Vinyl Chloride)en_US
dc.subjectPolymer Synthesisen_US
dc.subjectThermal-Degradationen_US
dc.subjectPolypropyleneen_US
dc.subjectCopolymersen_US
dc.subjectDiameteren_US
dc.subjectFibersen_US
dc.titleBile acid bearing poly (vinyl chloride) nanofibers by combination of CuAAC click chemistry and electrospinning processen_US
dc.typeArticleen_US

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