Comparison of corneal endothelial cell analysis in patients with uveitis and healthy subjects

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dc.authoridGüçlü, Hande/0000-0002-3021-0493
dc.authorwosidGüçlü, Hande/AAW-9756-2020
dc.contributor.authorGuclu, Hande
dc.contributor.authorGurlu, Vuslat
dc.date.accessioned2024-06-12T11:15:28Z
dc.date.available2024-06-12T11:15:28Z
dc.date.issued2019
dc.departmentTrakya Üniversitesien_US
dc.description.abstractPurposeThe aim of this study is to investigate the effect of uveitis in corneal endothelial cell number and morphology by non-contact specular microscopy.MethodsOur cross-sectional study was performed on 56 eyes of uveitis patients and 53 eyes of healthy subjects. Non-contact specular microscopy was performed to all subjects. The cell density (CD), coefficient of variation, cell minimum area (Min) and cell maximum area (Max), the average of cell size (AVG), percent of hexagonality (HEX%), central corneal thickness (CCT), intraocular pressure (IOP) during uveitis and during remission were measured and compared between two groups.ResultsThe mean endothelial cell analysis of the patients was 2540619 cells/mm(2), and the mean endothelial cell analysis of the control group was 2834 +/- 413 cells/mm(2). The difference was statistically significant between the groups (p=0.01). There was a statistically significant difference between two groups in terms of Max, Min, AVG, and HEX values. However, there was no difference in terms of CCT between two groups. There was a significant negative correlation between CD and IOP during uveitis attack. There was a significant negative correlation between the anterior chamber cell value and CD.Conclusion Our results suggested that uveitis affected endothelial cell density, cell size and shape but not the corneal thickness without being influenced by the duration and number of attacks. Increased IOP during uveitis and anterior chamber cell value had an important role on CD in patients with uveitis.en_US
dc.identifier.doi10.1007/s10792-017-0809-7
dc.identifier.endpage294en_US
dc.identifier.issn0165-5701
dc.identifier.issn1573-2630
dc.identifier.issue2en_US
dc.identifier.pmid29256169en_US
dc.identifier.scopus2-s2.0-85038364984en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage287en_US
dc.identifier.urihttps://doi.org/10.1007/s10792-017-0809-7
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23951
dc.identifier.volume39en_US
dc.identifier.wosWOS:000461164800004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSpecular Microscopyen_US
dc.subjectEndothelial Cell Densityen_US
dc.subjectCoefficient Of Variationen_US
dc.subjectThe Average Of Cell Sizeen_US
dc.subjectPercent Of Hexagonalityen_US
dc.subjectNoncontact Specular Microscopesen_US
dc.subjectContact-Lens Wearen_US
dc.subjectPseudoexfoliation Syndromeen_US
dc.subjectThicknessen_US
dc.subjectSp-2000pen_US
dc.subjectPhotometryen_US
dc.subjectSmokingen_US
dc.subjectDiseaseen_US
dc.titleComparison of corneal endothelial cell analysis in patients with uveitis and healthy subjectsen_US
dc.typeArticleen_US

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