The Clinical Significance of Incidental Parotid Uptake in a PET/CT Study: A Diagnostic Algorithm

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dc.contributor.authorUstun, Funda
dc.contributor.authorTastekin, Ebru
dc.contributor.authorTas, Abdullah
dc.contributor.authorAltun, Gulay Durmus
dc.date.accessioned2024-06-12T11:03:45Z
dc.date.available2024-06-12T11:03:45Z
dc.date.issued2019
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground: Patients diagnosed with cancer do not have sufficient clinical data for the management of incidental parotid lesions. We aimed to reveal the importance of randomized parotid lesions encountered during oncologic F-18 fluorodeoxyglucose positron emission tomography (FDG PET/CT) imaging in our clinical practice and the diagnostic algorithm of such lesions. Methods: We performed a database search of PET/CT records generated from 2009 to 2015 for parotid in reports of patients who underwent PET/CT examination for a known malignancy elsewhere, or cancer screening. Results: Incidental parotid FDG uptake on PET/CT had a prevalence of 1.1%. The incidence of parotid metastasis in our series was 36.4%, and 75% of them had malign melanoma metastasis. Of the 11 cases, 5 were of Warthin tumours, and Warthin tumours showed stronger GLUT1 expression than metastatic parotid lesions. Conclusion: In patients with malignancy elsewhere, focal involvement of FDG by the parotid gland, especially if malignant melanoma or SCC is absent, should not be considered a metastatic disease without histopathologic confirmation. If parotid disease would change the patient's treatment plan and disease stage, the parotid lesion should be evaluated by additional methods, such as fine needle aspiration biopsy.en_US
dc.identifier.doi10.2174/1573405614666171213160244
dc.identifier.endpage333en_US
dc.identifier.issn1573-4056
dc.identifier.issn1875-6603
dc.identifier.issue3en_US
dc.identifier.pmid31989884en_US
dc.identifier.scopus2-s2.0-85068425042en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage326en_US
dc.identifier.urihttps://doi.org/10.2174/1573405614666171213160244
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21776
dc.identifier.volume15en_US
dc.identifier.wosWOS:000459552600009en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBentham Science Publ Ltden_US
dc.relation.ispartofCurrent Medical Imaging Reviewsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIncidentalomaen_US
dc.subjectParotisen_US
dc.subjectWarthinen_US
dc.subjectFDG PET/CTen_US
dc.subjectMetastaticen_US
dc.subjectCancer Screeningen_US
dc.subjectPositron-Emission-Tomographyen_US
dc.subjectFocal Fdg Uptakeen_US
dc.subjectWarthins Tumoren_US
dc.subjectGlut1 Expressionen_US
dc.subjectGlanden_US
dc.subjectHeaden_US
dc.subjectMetastasisen_US
dc.subjectMelanomaen_US
dc.titleThe Clinical Significance of Incidental Parotid Uptake in a PET/CT Study: A Diagnostic Algorithmen_US
dc.typeArticleen_US

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