Subclinical atherosclerosis in gouty arthritis patients: a comparative study

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dc.authorwosidCakir, Necati/AAG-7283-2019
dc.contributor.authorCukurova, Selcuk
dc.contributor.authorPamuk, Omer Nuri
dc.contributor.authorUnlu, Ercument
dc.contributor.authorPamuk, Gulsum Emel
dc.contributor.authorCakir, Necati
dc.date.accessioned2024-06-12T11:02:47Z
dc.date.available2024-06-12T11:02:47Z
dc.date.issued2012
dc.departmentTrakya Üniversitesien_US
dc.description.abstractWe evaluated the incidence of subclinical atherosclerosis and associated factors in our gouty arthritis patients. We included 55 gouty arthritis patients diagnosed at our center within the last 4 years. The control group included 41 patients with rheumatoid arthritis (RA) and 34 patients with asymptomatic hyperuricemia (AHU). Atherosclerotic risk factors were determined in all subjects. Carotid intima-media thickness (IMT) and the presence of plaques were evaluated by B-mode ultrasonography. The carotid IMT in gouty arthritis patients (0.730 +/- 0.19) was significantly higher than in AHU subjects (0.616 +/- 0.12) (P = 0.004) and tended to be higher than the RA group (0.669 +/- 0.17) (P = 0.1). Atheromatous plaques were significantly more frequent in gouty arthritis patients (16 cases, 29.1%) than in RA patients (5 cases, 12.2%) and AHU subjects (3 cases, 8.8%) (P values, 0.05 and 0.023). Gout patients with plaques were older (P = 0.006) and tended to have tophi more frequently (P = 0.06). Logistic regression analysis showed that age (OR: 1.3, 95% CI: 1.02-1.54) and the presence of tophi (OR: 12.5, 95% CI: 1.2-140) were independent risk factors for the presence of plaques. Gouty arthritis bears a higher risk of atherosclerosis than both RA and AHU.en_US
dc.identifier.doi10.1007/s00296-011-1900-4
dc.identifier.endpage1773en_US
dc.identifier.issn0172-8172
dc.identifier.issn1437-160X
dc.identifier.issue6en_US
dc.identifier.pmid21442166en_US
dc.identifier.scopus2-s2.0-84863864023en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1769en_US
dc.identifier.urihttps://doi.org/10.1007/s00296-011-1900-4
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21406
dc.identifier.volume32en_US
dc.identifier.wosWOS:000305680300043en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofRheumatology Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGouty Arthritisen_US
dc.subjectAtherosclerosisen_US
dc.subjectAsymptomatic Hyperuricemiaen_US
dc.subjectRheumatoid Arthritisen_US
dc.subjectSystemic-Lupus-Erythematosusen_US
dc.subjectAcute Myocardial-Infarctionen_US
dc.subjectCoronary-Artery-Diseaseen_US
dc.subjectSerum Uric-Aciden_US
dc.subjectMetabolic Syndromeen_US
dc.subjectHeart-Diseaseen_US
dc.subjectCardiovascular-Diseaseen_US
dc.subjectRheumatoid-Arthritisen_US
dc.subjectEndothelial Functionen_US
dc.subjectInflammationen_US
dc.titleSubclinical atherosclerosis in gouty arthritis patients: a comparative studyen_US
dc.typeArticleen_US

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