In Vitro effects of pesticide exposure on Bovine liver catalase activity
Küçük Resim Yok
Tarih
2016
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Bulgarian Acad Science
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this work we investigated the inhibitory effect of Deltamethrin, Dichlorvos, Malathion and Lambdacyhalothrin on bovine liver catalase (CAT) activity. We observed that the inhibition of enzyme increased with increasing concentrations of the pesticides from 0 to 250 ppm. The Kinetics conformed to the Michaelis-Menten model and a Lineweaver-Burk graph of CAT was drawn. To identify the inhibition type, Vmax and Km were calculated at different concentrations of Deltamethrin, Dichlorvos, Malathion and Lambdacyhalothrin. It was documented that dichlorvos and malathion inhibited CAT competitively, whereas deltamethrin and Lambda-cyhalothrin inhibition over CAT were non-competitive.
Açıklama
Anahtar Kelimeler
Deltamethrin, Dichlorvos, Lambda-Cyhalothrin, Malathion, Catalase, Inhibition, Pesticide, Induced Oxidative Stress
Kaynak
Bulgarian Chemical Communications
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
48
Sayı
4
