Note of nitric oxide on the blood and immune system
Küçük Resim Yok
Tarih
2001
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this review, role of nitric oxide (NO) on the blood and immune system have been reviewed. NO is produced from L-arginine by the enzyme nitric oxide synthase (NOS). NOS isoform have been divided into two categories with different regulation and activities. The constitutive isoform is neuronal or enothelial cells are always present. The inducible NOS isoform in macrophages and hepatocytes is normally absent. The inducible NOS enzyme is produced by specific cytokines. NO reduces clotting by acting directly on platelets. NO has also been found inside platelets. NO kills or inhibits the growth of many pathogens, including bacteria, fungi and parasites. The role of NO in the immune system in nonspesific and damages any cell or pathogen.
Açıklama
Anahtar Kelimeler
Arginine; Cytokine; Isoenzyme; Nitric Oxide; Nitric Oxide Synthase; Blood; Blood Clotting; Endothelium Cell; Enzyme Activity; Enzyme Regulation; Immune System; Infection; Liver Cell; Macrophage; Nerve Cell; Nitrogen Metabolism; Review; Thrombocyte
Kaynak
SENDROM
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
13
Sayı
6
