Evaluation of vasomotor reactivity by transcranial Doppler sonography in patients with acute stroke who have symptomatic intracranial and extracranial stenosis

dc.contributor.authorUzunca, Ilkay
dc.contributor.authorAsil, Talip
dc.contributor.authorBalci, Kemal
dc.contributor.authorUtku, Ufuk
dc.date.accessioned2024-06-12T11:07:27Z
dc.date.available2024-06-12T11:07:27Z
dc.date.issued2007
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective. In patients with large artery disease, determining the cerebral hemodynamic state and following its alterations may be a good marker for predicting long-term outcome. The aim of our study was to compare the changes in vasomotor reactivity (VMR) of patients with symptomatic intracranial and extracranial artery stenosis. We also examined whether VMR after stroke influences the long-term prognosis for these patients. Methods. Forty-one patients were included in the study. To determine the cerebral hemodynamic state, transcranial Doppler ultrasound examinations and acetazolamide tests were performed after acute stroke and repeated after 6 months. We compared the VMR on admission and at 6 months, together with changes in VMR, of the patients with symptomatic intracranial and extracranial artery stenosis. By calculating the Barthel index at 6 months, We examined whether VMR had an effect on an improvement in their quality of life. Results. We observed a significantly higher initial VMR of the ipsilateral hemisphere in patients with intracranial stenosis (22.4 +/- 9.1 versus 13.4 +/- 12.8; P = .013). At 6 months, the VMR obtained from the ipsilateral hemisphere was better in patients with extracranial stenosis than in the patients with intracranial stenosis (P = .01). The ipsilateral VMR measured on admission showed a positive correlation with the Barthel index at 6 months (P = .007; r = 0.434). Conclusions. Our study showed that VMR in patients with acute stroke who have extracranial and intracranial artery stenosis measured by using a transcranial Doppler examination may have value in predicting long-term outcome.en_US
dc.identifier.doi10.7863/jum.2007.26.2.179
dc.identifier.endpage185en_US
dc.identifier.issn0278-4297
dc.identifier.issn1550-9613
dc.identifier.issue2en_US
dc.identifier.pmid17255179en_US
dc.identifier.scopus2-s2.0-33846683297en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage179en_US
dc.identifier.urihttps://doi.org/10.7863/jum.2007.26.2.179
dc.identifier.urihttps://hdl.handle.net/20.500.14551/22053
dc.identifier.volume26en_US
dc.identifier.wosWOS:000243776800005en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal Of Ultrasound In Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLarge Artery Atherothrombosisen_US
dc.subjectTranscranial Doppler Examinationen_US
dc.subjectVasomotor Reactivityen_US
dc.subjectCerebral-Artery Occlusionen_US
dc.subjectBlood-Flowen_US
dc.subjectAcetazolamideen_US
dc.subjectVasodilationen_US
dc.subjectReserveen_US
dc.subjectBrainen_US
dc.titleEvaluation of vasomotor reactivity by transcranial Doppler sonography in patients with acute stroke who have symptomatic intracranial and extracranial stenosisen_US
dc.typeArticleen_US

Dosyalar