Microwave ablation of symptomatic benign thyroid nodules: Short- and long-term effects on thyroid function tests, thyroglobulin and thyroid autoantibodies

dc.authoridErtürk, Mehmet Sercan/0000-0002-0411-553X
dc.authoridCelik, Mehmet/0000-0001-7364-370X
dc.authoridUcar, Havva/0000-0001-7572-444X
dc.authorwosidErtürk, Mehmet Sercan/AFS-7683-2022
dc.authorwosidCelik, Mehmet/AAA-8773-2021
dc.contributor.authorErturk, Mehmet Sercan
dc.contributor.authorCekic, Bulent
dc.contributor.authorCelik, Mehmet
dc.contributor.authorUcar, Havva
dc.date.accessioned2024-06-12T11:19:06Z
dc.date.available2024-06-12T11:19:06Z
dc.date.issued2021
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective Microwave ablation therapy has been attracting great attention due to its advantages such as low complication rate, good cosmetic results and effective nodule shrinking. Although the effect of thermal ablation therapy on the nodule volume reduction rate has been shown several studies, a limited number of papers have been reported for the effects of microwave ablation (MWA) on thyroid function tests. The aim of this study was to investigate the short- and long-term effects of MWA therapy on thyroid function tests (TFTs), thyroglobulin (Tg) and thyroid autoantibodies in euthyroid patients. Design, patients and measurements Demographic data of the patients, TFTs, Tg, thyroid autoantibodies and thyroid volume of the nodules were recorded before the procedure and follow-up. Any differences in serum thyroid hormone levels were investigated in pre-, post- and 6-month follow-up periods before and after MWA. Results The difference between all thyroid hormone levels at pre MWA and 24 h after MWA was statistically significant (p < .001). FT3 (4.62) pmol/L and FT4 (10.81) pmol/L median levels increased significantly (p < .001), while thyrotropin (TSH) levels decreased at 24 h after MWA (p < .001). Thyroid antibodies levels were not statistically different at 6-month (p > .05), whereas Tg levels decreased (p < .001) compared to pre MWA. Conclusions While no significant effect was observed at 6 month, the effect of MWA on thyroid function tests was prominent at 24 h.en_US
dc.identifier.doi10.1111/cen.14348
dc.identifier.endpage683en_US
dc.identifier.issn0300-0664
dc.identifier.issn1365-2265
dc.identifier.issue4en_US
dc.identifier.pmid33020965en_US
dc.identifier.scopus2-s2.0-85092734591en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage677en_US
dc.identifier.urihttps://doi.org/10.1111/cen.14348
dc.identifier.urihttps://hdl.handle.net/20.500.14551/25079
dc.identifier.volume94en_US
dc.identifier.wosWOS:000581654700001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofClinical Endocrinologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectImaging Follow-Upen_US
dc.subjectRadiofrequency Ablationen_US
dc.subjectThermal Ablationen_US
dc.subjectManagementen_US
dc.subjectPrinciplesen_US
dc.subjectSafetyen_US
dc.subjectLaseren_US
dc.titleMicrowave ablation of symptomatic benign thyroid nodules: Short- and long-term effects on thyroid function tests, thyroglobulin and thyroid autoantibodiesen_US
dc.typeArticleen_US

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