Respiratory syncytial virus epidemiology in Turkey

dc.authorscopusid7004528527
dc.authorscopusid7003829656
dc.authorscopusid57220513488
dc.authorscopusid7003640007
dc.authorscopusid11940118100
dc.authorscopusid57207515080
dc.authorscopusid55923807300
dc.contributor.authorKanra G.
dc.contributor.authorTezcan S.
dc.contributor.authorYilmaz G.
dc.contributor.authorAcunas B.
dc.contributor.authorAslan Ş.
dc.contributor.authorAslan Y.
dc.contributor.authorBelet N.
dc.date.accessioned2024-06-12T10:27:57Z
dc.date.available2024-06-12T10:27:57Z
dc.date.issued2005
dc.description.abstractRespiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infections in infants and young children worldwide. This study was conducted to determine the prevalence of RSV among high-risk children admitted with respiratory symptoms in a developing country. This is a multicenter study conducted among children less than 24 months of age and admitted to the hospital with respiratory symptoms. The inclusion criteria included: lower respiratory tract symptoms on admission, gestational age less than 35 weeks, and admission age less than six months, or children less than 24 months of age with a diagnosis of bronchopulmonary dysplasia requiring medical treatment or intervention during the last six months or with an uncorrected congenital heart disease (other than patent ductus arteriosus). Nasopharyngeal samples were obtained with one of the three standard methods: nasopharyngeal aspirate, nasopharyngeal wash or nasopharyngeal swab. RSV antigen was determined by enzyme immunoassay using Abbott TESTPACK RSV (No. 8100/2027-16). Statistical analysis was performed using Student's t-test and chi-square test. In this study, 332 children (135 females, 40.7%; 197 males, 59.3%) were included, and the nasopharyngeal specimens of 98 (29.5%) children were determined to be RSV-positive. There were no differences in sex, age of gestation, age of admission, family education, number of siblings and smoking at home for RSV-positive and -negative cases. Furthermore, underlying disease and duration of hospital and intensive care unit stay were similar among groups. Only otitis media was more common among RSV-positive cases. No fatality at hospital was recorded. Frozen samples revealed more negative results. Most cases presented during winter and the number of RSV-positive cases was higher in cold and economically poor areas. Premature children and children with underlying medical con dition acquire RSV irrespective of other sociodemographic risk factors, and most of them are hospitalized. Thus, an RSV vaccine seems the most effective mode of protection to decrease morbidity and mortality.en_US
dc.identifier.endpage308en_US
dc.identifier.issn0041-4301
dc.identifier.issue4en_US
dc.identifier.pmid16363337en_US
dc.identifier.scopus2-s2.0-31344441432en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage303en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/17011
dc.identifier.volume47en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEpidemiology; Respiratory Syncytial Virusen_US
dc.subjectVirus Antigen; Age Distribution; Antigen Detection; Article; Chi Square Test; Congestive Heart Failure; Controlled Study; Cystic Fibrosis; Demography; Disease Association; Enzyme Immunoassay; Female; Geographic Distribution; Gestational Age; Groups By Age; High Risk Population; Human; Immune Deficiency; Infant; Infant Mortality; Laboratory Diagnosis; Lung Dysplasia; Major Clinical Study; Male; Morbidity; Nose Smear; Population Distribution; Preschool Child; Prevalence; Respiratory Syncytial Pneumovirus; Risk Assessment; Risk Factor; Statistical Analysis; Statistical Significance; Student T Test; Turkey (Republic); Virus Infection; Comorbidity; Female; Humans; Infant; Length Of Stay; Male; Otitis Media; Prevalence; Prospective Studies; Respiratory Syncytial Virus Infections; Turkeyen_US
dc.titleRespiratory syncytial virus epidemiology in Turkeyen_US
dc.typeArticleen_US

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