Factors determining the treatment ineffectiveness in multiple sclerosis

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dc.contributor.authorGuler, Sibel
dc.date.accessioned2024-06-12T11:08:49Z
dc.date.available2024-06-12T11:08:49Z
dc.date.issued2022
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground In patients with multiple sclerosis (MS), the suboptimal response should be well evaluated at every step of treatment. Review Summary Determining patients with moderate or high activity and suboptimal response to treatment (clinical variables, MRI activity, perception of the patient and physician, side effects, serious risks, etc.) and timely intervention in the treatment are very important in achieving the desired effectiveness in the long term. Within the early stages, there is a limited time interval for effective treatment of MS patients. During this time, intervention is critical to achieve long-term positive results. After diagnosis, an early and individualized specific treatment for MS, depending on the severity of the disease, can prevent radiological and physical disability in the medium/long term. Conclusions With the emergence of a number of new treatments each with their own benefits and risks, a change in the nature of interactions between patients and MS physicians has been anticipated and will be required in the patient-related clinical decision-making process in the developing MS landscape.en_US
dc.identifier.doi10.1080/01616412.2021.1967680
dc.identifier.endpage185en_US
dc.identifier.issn0161-6412
dc.identifier.issn1743-1328
dc.identifier.issue2en_US
dc.identifier.pmid34396921en_US
dc.identifier.scopus2-s2.0-85112553082en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage177en_US
dc.identifier.urihttps://doi.org/10.1080/01616412.2021.1967680
dc.identifier.urihttps://hdl.handle.net/20.500.14551/22581
dc.identifier.volume44en_US
dc.identifier.wosWOS:000685335000001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofNeurological Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMultiple Sclerosisen_US
dc.subjectTreatment Unresponsivenessen_US
dc.subjectPrognosisen_US
dc.subjectIndividual Specific Treatmenten_US
dc.subjectTreatment Failureen_US
dc.subjectDisease-Activityen_US
dc.subjectInterferon-Betaen_US
dc.subjectDisabilityen_US
dc.subjectRecommendationsen_US
dc.subjectProgressionen_US
dc.subjectGuidelinesen_US
dc.titleFactors determining the treatment ineffectiveness in multiple sclerosisen_US
dc.typeArticleen_US

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