Effects of intra-abdominal pressure on liver function assessed with the LiMON in critically ill patients

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dc.contributor.authorInal, Mehmet Turan
dc.contributor.authorMemis, Dilek
dc.contributor.authorSezer, Y. Atakan
dc.contributor.authorAtalay, Meltem
dc.contributor.authorKarakoc, Abdullah
dc.contributor.authorSut, Necdet
dc.date.accessioned2024-06-12T11:19:36Z
dc.date.available2024-06-12T11:19:36Z
dc.date.issued2011
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground: Intra-abdominal pressure (IAP) and intra-abdominal hypertension (IAH) are associated with significant morbidity and mortality in critically ill patients. Our aim was to assess the effects of IAH on liver function using the noninvasive liver function monitoring system LiMON and to assess the prognostic value of IAP in critically ill patients. Methods: We conducted a retrospective analysis of critically ill patients who were treated in the intensive care unit (ICU). The IAP and indocyanine green plasma disappearance rate (ICG-PDR) measurements were made within 24 hours after admission to the ICU and repeated 12 hours later. Intra-abdominal pressure was measured via a Foley bladder catheter, and ICG elimination tests were conducted concurrently using the LiMON. Results: We included 30 critically ill patients (17 women and 13 men aged 28-89 yr) in our analysis. Statistical analysis showed that the baseline IAP values were significantly higher among nonsurvivors than survivors (19.38 [standard deviation; SD 2.08] v. 13.07 [SD 0.99]). The twelfth-hour IAP values were higher than baseline measurements among nonsurvivors (21.50 [SD 1.96]) and lower than baseline measurements among survivors (11.71 [SD 1.54]); the difference between groups was significant (p < 0.001). The baseline ICG-PDR values were significantly lower among nonsurvivors than survivors (10.86 [SD 3.35] v. 24.51 [SD 6.78]), and the twelfth-hour ICG-PDR values were decreased in all groups; the difference between groups was significant (p < 0.001). Conclusion: Our results suggest that measurement of ICG-PDR with the LiMON is a good predictor of the effects of IAP on liver function and, thus, can be recommended for the evaluation of critically ill patients.en_US
dc.identifier.doi10.1503/cjs.042709
dc.identifier.endpage166en_US
dc.identifier.issn0008-428X
dc.identifier.issn1488-2310
dc.identifier.issue3en_US
dc.identifier.pmid21443832en_US
dc.identifier.scopus2-s2.0-79959240818en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage161en_US
dc.identifier.urihttps://doi.org/10.1503/cjs.042709
dc.identifier.urihttps://hdl.handle.net/20.500.14551/25274
dc.identifier.volume54en_US
dc.identifier.wosWOS:000290999700008en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherCma-Canadian Medical Assocen_US
dc.relation.ispartofCanadian Journal Of Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPlasma Disappearance Rateen_US
dc.subjectAbdominal Compartment Syndromeen_US
dc.subjectIndocyanine Green Clearanceen_US
dc.subjectInternational-Conferenceen_US
dc.subjectInflammatory Responsesen_US
dc.subjectHypertensionen_US
dc.subjectDexmedetomidineen_US
dc.subjectTransplantationen_US
dc.subjectHemodynamicsen_US
dc.subjectKineticsen_US
dc.titleEffects of intra-abdominal pressure on liver function assessed with the LiMON in critically ill patientsen_US
dc.typeArticleen_US

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