Assessment of the New 2012 EULAR/ACR Clinical Classification Criteria for Polymyalgia Rheumatica: A Prospective Multicenter Study

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dc.authoridOzen, Gulsen/0000-0002-5423-393X
dc.authoridOrhan, Kevser/0000-0001-8639-751X
dc.authoridKeskin, Havva/0000-0003-1794-4473
dc.authoridATAGUNDUZ, PAMIR/0000-0002-6393-7461
dc.authoridAtagunduz, Pamir MP/0000-0002-6393-7461
dc.authoridAksu, Kenan/0000-0001-8889-2688
dc.authoridALIBAZ-ONER, FATMA/0000-0002-6653-1758
dc.authorwosidOzen, Gulsen/J-4547-2016
dc.authorwosidOrhan, Kevser/GVR-9735-2022
dc.authorwosidMurat, Sadiye/ABI-1603-2020
dc.authorwosidCan, Meryem/HLP-4890-2023
dc.authorwosidKeskin, Havva/ABH-3101-2021
dc.authorwosidATAGUNDUZ, PAMIR/AAM-6944-2021
dc.authorwosidAtagunduz, Pamir MP/B-1615-2018
dc.contributor.authorOzen, Gulsen
dc.contributor.authorInanc, Nevsun
dc.contributor.authorUnal, Ali Ugur
dc.contributor.authorBas, Seda
dc.contributor.authorKimyon, Gezmis
dc.contributor.authorKisacik, Bunyamin
dc.contributor.authorOnat, Ahmet Mesut
dc.date.accessioned2024-06-12T11:12:35Z
dc.date.available2024-06-12T11:12:35Z
dc.date.issued2016
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective. To assess the performance of the new 2012 provisional European League Against Rheumatism (EULAR)/ American College of Rheumatology (ACR) polymyalgia rheumatica (PMR) clinical classification criteria in discriminating PMR from other mimicking conditions compared with the previous 5 diagnostic criteria in a multicenter prospective study. Methods. Patients older than 50 years, presenting with new-onset bilateral shoulder pain with elevated acute-phase reactants (APR), were assessed for the fulfillment of the new and old classification/diagnostic criteria sets for PMR. At the end of the 1-year followup, 133 patients were diagnosed with PMR (expert opinion) and 142 with non-PMR conditions [69 rheumatoid arthritis (RA)]. Discriminating capacity, sensitivity, and specificity of the criteria sets were estimated. Results. Discriminating capacity of the new clinical criteria for PMR from non-PMR conditions and RA as estimated by area under the curve (AUC) were good with AUC of 0.736 and 0.781, respectively. The new criteria had a sensitivity of 89.5% and a specificity of 57.7% when tested against all non-PMR cases. When tested against all RA, seropositive RA, seronegative RA, and non-RA control patients, specificity changed to 66.7%, 100%, 20.7%, and 49.3%, respectively. Except for the Bird criteria, the 4 previous criteria had lower sensitivity and higher specificity (ranging from 83%-93%) compared with the new clinical criteria in discriminating PMR from all other controls. Conclusion. The new 2012 EULAR/ ACR clinical classification criteria for PMR is highly sensitive; however, its ability to discriminate PMR from other inflammatory/noninflammatory shoulder conditions, especially from seronegative RA, is not adequate. Imaging and other modifications such as cutoff values for APR might increase the specificity of the criteria.en_US
dc.identifier.doi10.3899/jrheum.151103
dc.identifier.endpage900en_US
dc.identifier.issn0315-162X
dc.identifier.issn1499-2752
dc.identifier.issue5en_US
dc.identifier.pmid26834222en_US
dc.identifier.scopus2-s2.0-84969262510en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage893en_US
dc.identifier.urihttps://doi.org/10.3899/jrheum.151103
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23225
dc.identifier.volume43en_US
dc.identifier.wosWOS:000380854200011en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherJ Rheumatol Publ Coen_US
dc.relation.ispartofJournal Of Rheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPOLYMYALGIA RHEUMATICAen_US
dc.subjectCLASSIFICATION CRITERIAen_US
dc.subjectRHEUMATOID ARTHRITISen_US
dc.subjectCitrullinated Peptide Antibodiesen_US
dc.subjectErythrocyte Sedimentation-Rateen_US
dc.subjectGiant-Cell Arteritisen_US
dc.subjectTemporal Arteritisen_US
dc.subjectDifferential-Diagnosisen_US
dc.subjectFollow-Upen_US
dc.subjectArthritisen_US
dc.subjectOnseten_US
dc.subjectUltrasounden_US
dc.subjectShoulderen_US
dc.titleAssessment of the New 2012 EULAR/ACR Clinical Classification Criteria for Polymyalgia Rheumatica: A Prospective Multicenter Studyen_US
dc.typeArticleen_US

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