Investigation of photophysical behaviours and antimicrobial activity of novel benzo-15-crown-5 substituted coumarin and chromone derivatives
Küçük Resim Yok
Tarih
2020
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Two different series of crown ether compounds (4-11) were synthesized by the reactions of 4',5'-bis(bromomethyl)benzo-15-crown-5 (3) and 4'-amino-benzo-15-crown-5 with hydroxycoumarin and chromone derivatives. Coumarin-crown ether compounds (4 and 5) were synthesized by the reactions of 4',5'-bis(bromomethyl)benzo-15-crown-5 (3) with 4-hydroxycoumarin and 7-hydroxycoumarin. Chromone-crown ether compounds (6-11), were synthesized by the condensation reactions of 4'-aminobenzo-15-crown-5 with 3-formylchromone and 6-methyl-3-formylchromone in different solvent media. Sodium and potassium complexes (4a-11a, 4b-11b) of new coumarin and chromone substituted benzo-15-crown-5 (B15C5) ligands (4-11) were prepared with NaSCN and KSCN, respectively. The syntheses of the novel crown ether compounds (4-11) and complexes (4a-11a, 4b-11b) were elucidated by the elemental analysis, FTIR, H-1 NMR, C-13 NMR and MS spectral data. The metal selectivities and effects of metal cations (Li+, Na+, K+, Mg2+, Ca2+, Ba2+, Ag+, Al3+, Cu2+, Zn2+, Ni2+, Pb2+, Fe3+, Cr3+) to the new crown ether compounds (4-11) were investigated by the absorption and fluorescence spectra. In addition, all of these substances were examined for antibacterial activity against pathogenic strains Listeria monocytogenes 4b, Staphylococcus aureus, Escherichia coli, Salmonella typhi H, Bacillus cereus, Micrococcus luteus, Shigella dysenteria type 2, Staphylococcus epidermidis, Proteus vulgaris, Klebsiella pneumonia sp., Serratia marcescens sp. and antifungal activity against Candida albicans. (C) 2019 Elsevier B.V. All rights reserved.
Açıklama
Anahtar Kelimeler
Crown Ethers, Coumarin, Chromone, Fluorescence, Metal Selectivity, Antimicrobial Activity, Double-Armed Benzo-15-Crown-5, Dna-Binding Properties, Crown-Ether, Cytotoxic Activity, Fluorescent Chemosensor, Schiff-Base, Spectroscopic Characterization, Ln(Iii) Complexes, Turn-On, Ni(Ii)
Kaynak
Journal Of Molecular Structure
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
1204
