Periprocedural cardiac troponin elevation: a potential indicator of enhanced ventricular threshold in permanent pacemaker recipients.

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dc.authoridTAYLAN, GOKAY/0000-0002-7015-4537
dc.authoridYILMAZTEPE, Mustafa/0000-0001-5328-5749
dc.authorwosidyilmaztepe, mustafa/AGE-8367-2022
dc.authorwosidAKTOZ, MERYEM/M-9023-2018
dc.authorwosidTAYLAN, GOKAY/HJZ-4693-2023
dc.contributor.authorUcar, Fatih Mehmet
dc.contributor.authorTaylan, Gokay
dc.contributor.authorYilmaztepe, Mustafa Adem
dc.contributor.authorAktoz, Meryem
dc.date.accessioned2024-06-12T10:55:43Z
dc.date.available2024-06-12T10:55:43Z
dc.date.issued2017
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground and aim: Permanent cardiac pacing is the most efficient treatment for patients with symptomatic bradycardia and high-degree atrioventricular (AV) block. For effective pacing, sensing and pacemaker battery longevity; ventricular pacing threshold (VPT) levels, lead impedance levels and Rwave amplitude levels must be desirable. We aimed to search the association between elevated serum troponin levels and VPT values in patients who has implanted single chamber permanent pacemaker. Materials and methods: We retrospectively analyzed a total of 109 patients (mean age: 78 +/- 7.1 years, 53.6% male) who underwent single chamber permanent pacemaker implantation for indications such high-degree atrioventricular block and sick sinus syndrome. Hematological and biochemical parameters were measured prior to pacemaker implantation. Additionally troponin I and high-sensitivity C-reactive protein (hs-CRP) were sampled about 12 hours after pacemaker implantation. Results: Over a median follow-up period of 17.3 months, 32 (29.3%) patients has positive troponin I levels after implantation. Troponin positive group has higher VPT values at the time of implantation (0.94 +/- 0.33 vs. 0.71 +/- 0.19, p<0.001) and at 30th day of implantation (0.69 +/- 0.16 V vs. 0.91 +/- 0.31 V, p<0.001). To identify in dependent risk factors for ventricular threshold values, a multivariate linear regression model was conducted and after implantation having positive troponin value (beta= 0.337, p= 0.01) and troponin elevation ratio (beta= 0.365, p<0.001) were found to be independent risk factors for ventricular threshold. Conclusion: Our results indicate that troponin I elevation after pacemaker implantation is associated with higher VPT values at the time of and the 30th day of implantation. For longevity of pacemaker batteries, low threshold values are preferable. To further extend the life of pacemakers, we recommend following patients more closely who has high troponin levels after permanent pace replacement.en_US
dc.identifier.endpage3698en_US
dc.identifier.issn0970-938X
dc.identifier.issn0976-1683
dc.identifier.issue8en_US
dc.identifier.startpage3693en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19528
dc.identifier.volume28en_US
dc.identifier.wosWOS:000403454800067en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherScientific Publishers Indiaen_US
dc.relation.ispartofBiomedical Research-Indiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCardiac Pacemakeren_US
dc.subjectTroponinen_US
dc.subjectVentricular Pacing Thresholden_US
dc.subjectSteroid-Eluting Electrodeen_US
dc.subjectAntibradycardia Pacemakeren_US
dc.subjectTransvenous Implantationen_US
dc.subjectLeadsen_US
dc.subjectInjuryen_US
dc.titlePeriprocedural cardiac troponin elevation: a potential indicator of enhanced ventricular threshold in permanent pacemaker recipients.en_US
dc.typeArticleen_US

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