Superparamagnetic iron oxide enhanced magnetic resonance imaging in the detection of malignant liver lesions

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dc.authorscopusid16041689500
dc.authorscopusid15069811700
dc.authorscopusid6505802591
dc.authorscopusid56008217600
dc.authorscopusid24462850000
dc.authorscopusid35564549100
dc.contributor.authorÇa?li B.
dc.contributor.authorTemizöz O.
dc.contributor.authorGençhellaç H.
dc.contributor.authorÜmit H.
dc.contributor.authorTosun A.
dc.contributor.authorÇakir B.
dc.date.accessioned2024-06-12T10:26:27Z
dc.date.available2024-06-12T10:26:27Z
dc.date.issued2011
dc.description.abstractObjective: To determine the value of superparamagnetic iron oxide (SPIO)-enhanced MR imaging in malignant liver lesions. Materials and Methods: Twenty patients with various hepatic masses or metastases were investigated with 1 tesla MR. T1-weighted FLASH and double- echo TSE T2-weighted sequences were applied before and after contrast injection. "Defining statistics" were prepared according to pre and postcontrast signal intensity measurements. Results: In this study there were 11 patients with metastases, 4 patients with hemangioma, 4 patients with HCC and one patient with a hemangioma and a metastasis at the same time. In cases wheret we found only hemangiomas, in all sequences, S/N ratios (p=0.043) and T2-weighted double-echo TSE with long TE SI change (p=0.043) were significant. While in the hemangiomas in T2-weighted double-echo TSE with long TE there is an decrease in the C/N ratios; in cases with metastasis and HCC, compared to other sequences significant increase in C/N ratio in T2-weighted double-echo TSE with short TE sequences was detected. Conclusion: SPIO-enhanced MR imaging can be used as a non-invasive radiologic technique for the detection focal liver lesions, to determine the number of lesions and also has a value in differentiating the benign lesions (especially hemangiomas) from primary tumors or metastatic malignant lesions. © Trakya University Faculty of Medicine.en_US
dc.identifier.doi10.5174/tutfd.2010.03880.2
dc.identifier.endpage292en_US
dc.identifier.issn2146-3123
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-80053342453en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage286en_US
dc.identifier.urihttps://doi.org/10.5174/tutfd.2010.03880.2
dc.identifier.urihttps://hdl.handle.net/20.500.14551/16857
dc.identifier.volume28en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherGalenos Publishing Houseen_US
dc.relation.ispartofBalkan Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectContrast-Noise Ratio; Mr Imaging; Superparamagnetic Iron Oxide (Spio); T1-Weighted Flash And T2-Weighted Double-Echo Tse Sequencesen_US
dc.subjectSuperparamagnetic Iron Oxide; Article; Clinical Article; Contrast Enhancement; Controlled Study; Diagnostic Value; Human; Liver Cell Carcinoma; Liver Hemangioma; Liver Injury; Liver Metastasis; Malignant Neoplastic Disease; Nuclear Magnetic Resonance Imaging; Signal Noise Ratioen_US
dc.titleSuperparamagnetic iron oxide enhanced magnetic resonance imaging in the detection of malignant liver lesionsen_US
dc.title.alternativeMalign karaci?er kitlelerinin saptanmasında süperparamanyetik demir oksit ile manyetik rezonans görüntülemeen_US
dc.typeArticleen_US

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