Effecting factors on survival in patients taking thrombolytic treatment due to massive pulmonary embolism

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dc.authoridTABAKOGLU, ERHAN/0000-0003-1315-4538
dc.authorwosid, Osman/AGR-7980-2022
dc.authorwosid, osman/HRD-6024-2023
dc.contributor.authorHatipoglu, Osman Nuri
dc.contributor.authorPerincek, Gokhan
dc.contributor.authorEdis, Ebru Cakir
dc.contributor.authorTabakoglu, Erhan
dc.contributor.authorAltiay, Gundeniz
dc.date.accessioned2024-06-12T11:08:08Z
dc.date.available2024-06-12T11:08:08Z
dc.date.issued2010
dc.departmentTrakya Üniversitesien_US
dc.description.abstractMassive pulmonary embolism (MPE) is a life threatening disease, thrombolytic treatment could save lives. The aims of this study are to identify early and late mortality rates in patients with MPE who received thrombolytic treatment, and mortality related risk factors. All the hospital records for the MPE patients who received thrombolytic treatment between 1998 and 2006 were retrospectively investigated. Pulmonary embolism was diagnosed through computed tomografi scan and V/P scintigraphy. Due to MPE, 21 women total 41 patients who undergo tPA or streptokinase were included in the study. Kaplan-Meier for the survival analysis and cox regression analysis for determining the mortality related independent risk factors were used. Dying while staying in hospital was accepted as early or hospital mortality, after discharge from hospital as late mortality. Out of 41 patients, 12 of them died while they are hospitalized (hospital mortality; 29%) 6 of them died after they were discharged (late mortality; 21%). The average survival time among discharged patients was 2304 days (95% confidence interval: 1725-2884). Among those patients who took streptokinase or tPA, late or early mortality rates (p>0.05) and survival time did not show significant difference (p=0.8908). The presence of arrhythmia [p=0.01; odds rate (OR): 6.25] and jugular vein distention (JVD) (p=0.03; OR: 6.25) for hospital mortality and multiple ongoing health problems for the late mortality were identified as the independent risk factors. For the hospital mortality, the presence of JVD or arrhythmia, for prognostic sensitivity, specificity, positive predictive value and negative predictive value were recorded as 75%, 79%, 60% and 88% respectively. In conclusion, the presence of arrhythmia and/or JVD on a patient with MPE is a negative prognostic factor for hospital mortality. The presence of other ongoing health problems influences the survival time of the discharged patients.en_US
dc.identifier.endpage277en_US
dc.identifier.issn0494-1373
dc.identifier.issue3en_US
dc.identifier.pmid21038137en_US
dc.identifier.scopus2-s2.0-77958102926en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage268en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/22308
dc.identifier.volume58en_US
dc.identifier.wosWOS:000421277100005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isotren_US
dc.publisherTurkish Assoc Tuberculosis & Thoraxen_US
dc.relation.ispartofTuberkuloz Ve Torak-Tuberculosis And Thoraxen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMassive Pulmonary Embolismen_US
dc.subjectThrombolytic Treatmenten_US
dc.subjectSurvivalen_US
dc.titleEffecting factors on survival in patients taking thrombolytic treatment due to massive pulmonary embolismen_US
dc.typeArticleen_US

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