A life-threatening infection: Fournier's gangrene
Küçük Resim Yok
Tarih
2002
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Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Fournier's gangrene is a life-threatening disorder in which infection of the perineum and scrotum spreads along fascial planes, causing soft tissue necrosis. If urgent surgery is delayed, the disease will soon result in septic shock, multiorgan failure, and death. In this study, we present 21 patients with Founder's gangrene who were treated in period between 1994 and 2001. Patients' charts were reviewed retrospectively and are discussed in the light of literature. All patients received aggressive surgical debridment. Penicillin or Ceftriaxone, aminoglicoside and metronidazole were administered intravenously. Of the 21 patients, 5 had scrotal carbuncle, 1 had urethral stricture, 1 had chronic indwelling urethral catheterization, 2 had perirectal abscess, and 1 had hemorrhoidectomy. In eleven patients we couldn't identify any cause. Twelve patients had diabetes mellitus, and two had chronic alcoholism. Escherichia coli was isolated in 12 purulent tissue cultures, and Bacteroides fragilis in eight. Seventeen patients survived, whereas four died. Founder's gangrene is considered a surgical emergency. Early surgical intervention is essential, as the gangrene can spread rapidly at rates reaching 2 mm per hour. So that Founder's gangrene is an abrupt, rapidly progressive, gangrenous infection of the external genitalia and perineum and is a real urologic emergency.
Açıklama
Anahtar Kelimeler
Fournier's Gangrene; Infection; Necrotizing Fasciitis; Penis; Scrotum, Aminoglycoside Antibiotic Agent; Ceftriaxone; Metronidazole; Penicillin G; Adult; Aged; Alcoholism; Article; Bacterium Isolate; Bacteroides Fragilis; Bladder Catheterization; Carbuncle; Clinical Article; Colostomy; Cystostomy; Death; Debridement; Diabetes Mellitus; Disease Association; Disease Course; Emergency Surgery; Escherichia Coli; Fournier Gangrene; Genital System; Hemorrhoidectomy; Human; Indwelling Catheter; Male; Medical Record; Orchiectomy; Penis Amputation; Perianal Abscess; Perineum; Retrospective Study; Scrotum; Survival; Tissue Culture; Urethra Stricture; Urinary Diversion; Adult; Aged; Alcoholism; Diabetes Complications; Fournier Gangrene; Genital Diseases, Male; Humans; Male; Middle Aged; Scrotum
Kaynak
International Urology and Nephrology
WoS Q Değeri
Scopus Q Değeri
Q2
Cilt
34
Sayı
3
