The relationship between coronary artery disease and uric acid levels in young patients with acute myocardial infarction
Küçük Resim Yok
Tarih
2008
Yazarlar
Dergi Başlığı
Dergi ISSN
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Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background: Serum uric acid concentrations are higher in patients with established coronary artery disease than in healthy controls. This study aimed to determine the role of uric acid in predetermining coronary artery disease in youngpatients with acute myocardial infarction (AMI). Methods: This study included 80 of 1612 patients who applied our hospital between January 2000 and December 2005. All of the patients were under 35 years old, diagnosed with AMI by clinical and laboratory findings, and had coronary angiography. The study population was divided into two groups, the first having critical coronary artery disease (group I) and the second having normal coronary arteries (group II). Then we compared these groups with age, body mass index, risk factors, serum protein C, protein S, antithrombin III, creatinine and uric acid levels. Results: Myocardial infarction was located in 65% anterior, 15% inferior, 15% inferiolateral and 5% high lateral, respectively. Forty five % of patients had critical coronary artery disease (group I, n = 36) and 55% had normal coronary arteries (group II, n = 44). There were no differences in the two groups with regard to body mass index, family history, hypertension, smoking, cholesterol level, triglyceride level and creatinine level, lack of protein C, lack of protein S or lack of antithrombin Iff. Serum uric acid levels were found to be higher in group I (7.0 ± ± 1.4 mg/dL) than in group II (4.9 ± 1.1 mg/dL,- p = 0. 003). Conclusions: This study showed that high serum uric acid levels were associated with critical coronary artery disease in young patients (< 35 years) with AMI. Copyright © 2008 Via Medica.
Açıklama
Anahtar Kelimeler
Acute Myocardial Infarction; Coronary Artery Disease; Uric Acid; Young Patients, Antithrombin Iii; Cholesterol; Creatinine; Fibrinolytic Agent; Protein C; Protein S; Triacylglycerol; Uric Acid; Acute Heart Infarction; Adult; Age; Angiocardiography; Article; Body Mass; Cardiovascular Risk; Cholesterol Blood Level; Cigarette Smoking; Clinical Assessment; Controlled Study; Coronary Artery Disease; Correlational Study; Creatinine Blood Level; Disease Marker; Disease Severity; Family History; Human; Hypertension; Laboratory Test; Major Clinical Study; Male; Protein Blood Level; Protein Determination; Risk Assessment; Risk Factor; Triacylglycerol Blood Level; Uric Acid Blood Level; Adult; Antithrombin Iii; Body Mass Index; Coronary Angiography; Coronary Artery Disease; Creatinine; Female; Humans; Male; Myocardial Infarction; Protein C; Protein S; Uric Acid
Kaynak
Cardiology Journal
WoS Q Değeri
Scopus Q Değeri
Q2
Cilt
15
Sayı
1
